scholarly journals Efficacy of Enamel Matrix Proteins in Periodontal Regeneration of Intraosseous Defects: An Umbrella Review

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Rubiel Marín Jaramillo ◽  
Sebastian Frías Tarón
2002 ◽  
Vol 81 (11) ◽  
pp. 776-783 ◽  
Author(s):  
P.M. Brett ◽  
M. Parkar ◽  
I. Olsen ◽  
M. Tonetti

Several studies have examined the role of enamel matrix proteins in root formation and periodontal regeneration, although most of these have focused on a few specific genes which had previously been implicated. However, recent advances in expressional profiling have made it possible to examine the range of genetic responses involved in these processes. In the present experiments, we have therefore utilized this technique to determine the effects of enamel matrix proteins on the gene activities of periodontal ligament cells in vitro. Such cells were found to have an elevated level of RNA synthesis compared with control cells. Moreover, hybridization of the cDNA prepared from this RNA to gene array filters showed that there was differential expression of 121 genes, most of which had not previously been associated with periodontal regeneration. Some of these selective changes in gene activity might thus reflect the fundamental events that underlie periodontal development.


2003 ◽  
Vol 74 (7) ◽  
pp. 1043-1055 ◽  
Author(s):  
D.L. Cochran ◽  
G.N. King ◽  
J. Schoolfield ◽  
D. Velasquez-Plata ◽  
J.T Mellonig ◽  
...  

2001 ◽  
Vol 63 (8) ◽  
pp. 889-894 ◽  
Author(s):  
Kazuhiro WATANABE ◽  
Masahiro KIKUCHI ◽  
Masahiro OKUMURA ◽  
Tsuyoshi KADOSAWA ◽  
Toru FUJINAGA

2003 ◽  
Vol 74 (9) ◽  
pp. 1269-1281 ◽  
Author(s):  
David L. Cochran ◽  
Archie Jones ◽  
Lars Heijl ◽  
James T. Mellonig ◽  
John Schoolfield ◽  
...  

2013 ◽  
Vol 9 (1) ◽  
pp. 4796-4805 ◽  
Author(s):  
Harsh D. Amin ◽  
Irwin Olsen ◽  
Jonathan C. Knowles ◽  
Michel Dard ◽  
Nikolaos Donos

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