A periodontal tissue regeneration strategy via biphasic release of zeolitic imidazolate framework-8 and FK506 using a uniaxial electrospun Janus nanofiber

Guided tissue regeneration (GTR) strategy is an effective approach to repair periodontal defect by using GTR membranes. However, the commercial GTR membranes still have limitations in periodontal tissue regeneration owing...

Treatment of localized gingival recession with chorion membrane- A case report

Aim of root coverage procedure is to restore the tissue margin to the Cemento-enamel junction. Many surgical techniques have been developed throughout the years and Guided tissue regeneration (GTR) based rootcoverage using different allograft membranes has been utilized to treat gingival recession with excellent results.This case report describes a case of gingival recession managed by chorion membrane with coronally advanced flap.

Observation on the Effect of Bone Grafting Alone and Guided Tissue Regeneration Combined with Bone Grafting to Repair Periodontal Intraosseous Defects

Objective. To investigate the curative effect of guided tissue regeneration (GTR) combined with bone grafting and improve the aesthetic appearance of patients’ gingiva. Methods. A total of 86 patients with periodontal intraosseous defects were selected from February 2019 to February 2021. All the patients were divided into a control group and an observation group according to the random number table, with 43 patients in each group. Bone grafting was performed in the control group, while GTR was additionally used in the observation group on the basis of the control group. The surgical data and follow-up data were collected and organized. The alveolar bone mineral density, the change in the height of the bone defect, plaque index (PLI), sulcus hemorrhage index (SBI), PD, gingival recession (GR), clinical attachment loss (CAL), and other relevant data of the two groups in 6 months before and after surgery were compared. Six months after surgery, the cosmetic morphology of the patient's gums in the soft tissues around her teeth was evaluated. Results. Six months after surgery, the alveolar bone density of patients in two groups increased compared with that before surgery, and the height of the bone defect decreased compared with that before surgery. The alveolar bone density of the observation group was higher than that of the control group, and the height of the bone defect was lower than that of the control group ( P < 0.05 ). Six months after surgery, the PLI, SBI, PD, and CAL of patients in both groups were lower than those before surgery, while the GR was higher than that before surgery. PD and CAL values in the observation group were lower than those in the control group, and GR was higher than that in the control group ( P < 0.05 ). Six months after surgery, there was no significant difference in PLI and SBI scores between the two groups ( P < 0.05 ). Six months after surgery, the gingival cosmetic scores of the two groups of patients were higher than those before surgery. The observation group was higher than the control group ( P < 0.05 ). Conclusion. GTR combined with bone grafting has a good effect in the repair of periodontal intraosseous defects and can effectively promote the reconstruction and recovery of periodontal intraosseous defects in patients. At the same time, it can significantly improve the aesthetic appearance of patients’ gums, with good clinical application value.

Technology Regeneration Guided with Fibrin Rica in Platelets in Implantodontia - A Literature Review

The tissue loss is one of the consequences of damage caused by tooth loss and consequently bone tissue, one of the techniques to minimize or even correct this damage is the use of platelet-rich fibrin-guided tissue regeneration. The use of biomaterials in order to replace bone deficiencies in the regions to be implanted should provide the capacity to regenerate bone tissue, as well as make the new bone structures functional. A bibliographic survey of articles published between 2013 and 2021, articles indexed in the Databases PubMed/MEDLINE, Scielo and Google Scholar, was carried out using the keywords “Fibrin-rich platelets”, "Periodontics", "Connective Tissue" and "Guided Tissue Regeneration". We found 206 articles published in the specified period, after reading the title and abstract, 17 potential articles were identified to be part of the literature review. The technique of using platelet-rich fibrin in dentistry has shown promising results, with low cost, easy execution and accelerated healing process. The limitations of the technique were found the short time to use the material and the small amount obtained after centrifugation.

Second Attempt of Guided Tissue Regeneration on a Previous Successfully Grafted Site with Periodontal Breakdown—A 5-Year Follow-up

Guided tissue regeneration (GTR) has been proven to promote attachment and regeneration of periodontal tissue. However, there is a 20 to 40% incidence of attachment loss on regenerated attachments reported in the literature. To my knowledge, this is the first case report on a second attempt in GTR on a previous successful grafted site with clinical attachment loss. A healthy 17-year-old Chinese male patient had GTR performed with xenograft particles and bovine resorbable membrane on his root-canal treated, fused upper right lateral incisor and upper right canine (#12-#13) in 2007. Probing depth on the mid-palatal region of #12-#13 was reduced to 4 mm and maintained for the next 4 years. But in the fifth year, probing depth increased to 11 mm with no endodontic symptoms, and a second attempt of GTR using the same materials was carried out. The probing depth at the surgical site was reduced to 4 mm and successfully maintained for another 5 years. Irregular maintenance and the presence of plaque retentive factor could have caused the clinical attachment loss on #12-#13. This case shows it is possible to attempt GTR on a previous successfully grafted site. GTR did not increase tissue resistance against periodontal breakdown. Hence, proper maintenance planning for GTR sites is important to prevent periodontal breakdown.

A regenerative approach to the classification of the defects in the periodontal and alveolar ridge

The efficacy and long-term outcomes of the procedure of guided tissue regeneration depend on the basic morphometric condition of the defect and the choice of the technical supplement and the technical approach to surgery. Hystoarchitectonics of defects can be presented as a simplified four-parameter classification for use in clinical and expert practice in addition to making decisions in the regenerative surgery of defects in the periodontal and alveolar ridge.

KERUSAKAN TULANG PADA KASUS ENDODONTIK-PERIODONTAL

Latar belakang. Masalah pulpa dan periodontal menyebabkan lebih dari 50% kehilangan gigi. Kasus pada laporan kasus ini merupakan lesi primer endodontik dan lesi sekunder periodontal dan secara klinis terdapat sinus tract. Kondisi ini merupakan kasus yang secara kolaborasi dikerjakan oleh bidang konservasi gigi dan bidang periodonsia untukmemdapatkan hasil yang maksimal. Kasus. Terdapat tiga kasus lesi endodonti-periodontal, dua merupakan kasus (gigi 21 dan 37) yang setelah beberapa tahun dilakukan perawatan saluran akar (PSA) mengalami pembentukan sinus tract, dan satu kasus (gigi 47) yang setelah PSA namun tidak memeperlihatkan perbaikan sinus tract yang terbentuk di gingiva. Tindakan bedah flap periodontal dilakukan untuk mencari penyebab, menghilangkan jaringan granulasi, dan memperbaiki kerusakan tulang alveolar yang terjadi. Seluruh kasus terlihat terdapat kerusakan tulang anguler di daerah furkasi pada gigi posterior (37 dan 47), dan daerah interdental pada gigi anterior (21); satu kasus (gigi 21) mengalami fenestrasi di fasial. Defek tulang anguler dan daerah fenestrasi setelah dibersihkan dari jaringan granulasi yang terinfeksi, diisi dengan graf tulang dan ditutup oleh membran pericardium sebagai guided tissue regeneration (GTR), kemudian dijahit. Kontrol 14 hari setelah tindakan bedah, sinus tract telah hilang dan warna gingiva normal. Kesimpulan. Lesi endodontik-periodontal yang memperlihatkan sinus tract yang persisten setelah perawatan saluran akar merupakan indikasi adanya kerusakan periodontal yang kompleks. Defek periodontal kompleks bisa diperbaiki dengan tindakan bedah regeneratif.Kata kunci. Lesi endodontik-periodontal, sinus tract, defek tulang anguler, fenestrasi Abstract Background. Dental pulp and periodontal problems account for more than 50% of tooth loss. The cases in this case report were primary endodontic lesions and secondary periodontal lesions and clinically contained a sinus tract. This report is a collaborative carried out by the conservative dentistry and periodontics to obtain maximum results. Case. There were three cases of endodontic-periodontal lesions, two were cases (teeth 21 and 37) where after several years of root canal treatment had sinus tract formation, and one case (tooth 47) after endodontic treatment but did not show any improvement in the sinus tract in the gingiva. Periodontal flap surgery is performed to find the cause, remove the granulation tissue, and repair the alveolar bone damage that has occurred. All cases showed angular bone defects in the furcation areas of the posterior teeth (37 and 47), and the interdental areas of the anterior teeth (21); one case (tooth 21) had facial fenestration. Angular bone defects and areas of fenestration after cleaning of infected granulation tissue, filled with bone graft and covered by pericardial membrane as guided tissue regeneration (GTR), then sutured. Control 14 days after surgery, the sinus tract was gone and the gingival color was normal. Conclusion. Endodontic-periodontal lesions showing persistent sinus tracts after root canal treatment are indicated of complex periodontal damage. Complex periodontal defects can be corrected with regenerative surgery.Keywords. endodontic-periodontal lesions, sinus tract, angular bone defect, fenestration

Guided Tissue Regeneration Treatment Yields Better Results in Class II Furcations in the Mandible Than in the Maxilla: A Retrospective Study

Absorbable porcine collagen membrane with a bovine bone graft can be considered for regenerative treatment in periodontal class II furcation defects. We evaluated the clinical efficacy of guided tissue regeneration (GTR) treatment with bovine bone xenograft and a porcine collagen membrane in molars with class II furcations. Probing depth (PD), clinical attachment level (CAL), and bone level (BL) were recorded at baseline and at 3, 6, and 9 months postoperatively. Thirty class II furcation defects from the lower and upper molars were assessed. Significant improvements in PD and CAL were observed from baseline to 9 months in all groups (p < 0.01). BL improved in all groups except group A in the upper molars in radiographic assessment (p < 0.05). The lower and upper molars showed PD reduction of 50.5% ± 7.44% and 46.2% ± 11.2%, respectively, at 9 months (p = 0.044). In furcations of 1–3 mm, the lower and upper molars showed PD reductions of 51.2% ± 4.49% and 36.5% ± 16.14%, respectively (p = 0.035). The lower and upper molars showed a CAL gain of 51.1% ± 4.64% and 33.6% ± 18.8%, respectively (p = 0.037). Thus, GTR with bovine bone graft and porcine collagen membrane yielded good results in class II furcations, with better results in the lower than in the upper molars.