scholarly journals Application of Blue Filters Increases the Usefulness of Moreland Test in Anomaloscopic Color Vision Assessment for Blue–Green Color Range

Author(s):  
Krzysztof Piotr Michalak ◽  
Jacek Zabel ◽  
Jan Olszewski ◽  
Paulina Wojtyła-Buciora ◽  
Anna Przekoracka-Krawczyk

The effect of blue light filters on the anomaloscopic examination was analyzed. Thirty subjects (18–43 y, 20 female, 10 male) without color vision disorders were examined in 4 filter conditions: no filter (F-0), Blue Control Hoya (F-BC), Med-1 JZO (F-Med1) and 450 Eschenbach (F-450). Both Rayleigh test (red–green axis) and Moreland test (blue–green axis) were performed. Application of F-BC filter shows negligible effect on color vision perception in both tests. Contrary to this, the application of strong F-450 filter causes significant shift in Moreland test towards tritanopy and the decrease in correlations of Moreland parameters with Rayleigh test parameters. The application of medium strong F-Med1 filter causes the slight shift in Moreland test towards the center of the Moreland scale and increases the Spearman correlations between Moreland and Rayleigh test parameters. This observation suggests that the about 15–40% reduction of blue diode intensity in the Moreland test may be beneficial in detecting mild changes in color vision perception in the blue-green axis and may improve its usefulness in evaluating the color vision perception disorders accompanying different illnesses, such as diabetes, glaucoma, neuritis optica, or cataract. The discussion concerning the modifications of Moreland test construction is also presented.

Genetics ◽  
2001 ◽  
Vol 158 (4) ◽  
pp. 1697-1710 ◽  
Author(s):  
Shozo Yokoyama ◽  
F Bernhard Radlwimmer

Abstract To better understand the evolution of red-green color vision in vertebrates, we inferred the amino acid sequences of the ancestral pigments of 11 selected visual pigments: the LWS pigments of cave fish (Astyanax fasciatus), frog (Xenopus laevis), chicken (Gallus gallus), chameleon (Anolis carolinensis), goat (Capra hircus), and human (Homo sapiens); and the MWS pigments of cave fish, gecko (Gekko gekko), mouse (Mus musculus), squirrel (Sciurus carolinensis), and human. We constructed these ancestral pigments by introducing the necessary mutations into contemporary pigments and evaluated their absorption spectra using an in vitro assay. The results show that the common ancestor of vertebrates and most other ancestors had LWS pigments. Multiple regression analyses of ancestral and contemporary MWS and LWS pigments show that single mutations S180A, H197Y, Y277F, T285A, A308S, and double mutations S180A/H197Y shift the λmax of the pigments by −7, −28, −8, −15, −27, and 11 nm, respectively. It is most likely that this “five-sites” rule is the molecular basis of spectral tuning in the MWS and LWS pigments during vertebrate evolution.


2016 ◽  
Vol 57 (8) ◽  
pp. 3853 ◽  
Author(s):  
Emily J. Patterson ◽  
Melissa Wilk ◽  
Christopher S. Langlo ◽  
Melissa Kasilian ◽  
Michael Ring ◽  
...  

Biochemistry ◽  
1993 ◽  
Vol 32 (9) ◽  
pp. 2125-2130 ◽  
Author(s):  
Zhiyan Wang ◽  
Ana B. Asenjo ◽  
Daniel D. Oprian

2018 ◽  
pp. 1499-1501
Author(s):  
Niloofar Yari ◽  
Sumayya J. Almarzouqi ◽  
Michael L. Morgan ◽  
Andrew G. Lee

2008 ◽  
Vol 37 ◽  
pp. 109-114 ◽  
Author(s):  
Kazuki Miyazaki ◽  
Teiko Kashiwada ◽  
Takaaki Hayashi ◽  
Takaaki Kitakawa ◽  
Akiko Kubo ◽  
...  

Science ◽  
1991 ◽  
Vol 252 (5008) ◽  
pp. 971-974 ◽  
Author(s):  
M Neitz ◽  
J Neitz ◽  
G. Jacobs

Author(s):  
Niloofar Yari ◽  
Sumayya J. Almarzouqi ◽  
Michael Morgan ◽  
Andrew G. Lee

2020 ◽  
Vol 46 (1) ◽  
pp. 7-20 ◽  
Author(s):  
Benjamin E. W. Evans ◽  
Marisa Rodriguez‐Carmona ◽  
John L. Barbur

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