scholarly journals Italian Expert Consensus on Clinical and Therapeutic Management of Multiple Chemical Sensitivity (MCS)

2021 ◽  
Vol 18 (21) ◽  
pp. 11294
Author(s):  
Giovanni Damiani ◽  
Marco Alessandrini ◽  
Daniela Caccamo ◽  
Andrea Cormano ◽  
Gianpaolo Guzzi ◽  
...  
Keyword(s):  
Signs And Symptoms ◽  
Multiple Chemical Sensitivity ◽  
Threshold Limit Value ◽  
Therapeutic Management ◽  
Chemical Sensitivity ◽  
Main Research ◽  
Limit Value ◽  
And Gender ◽  
Based Medicine ◽  
Multiple Chemical

Multiple chemical sensitivity (MCS) is a multisystem, recurrent, environmental disorder that flares in response to different exposures (i.e., pesticides, solvents, toxic metals and molds) under the threshold limit value (TLV) calculated for age and gender in the general population. MCS is a syndrome characterized by cutaneous, allergic, gastrointestinal, rheumatological, endocrinological, cardiological and neurological signs and symptoms. We performed a systematic review of the literature to summarize the current clinical and therapeutic evidence and then oriented an eDelphi consensus. Four main research domains were identified (diagnosis, treatment, hospitalization and emergency) and discussed by 10 experts and an MCS patient. Thus, the first Italian MCS consensus had the double aim: (a) to improve MCS knowledge among healthcare workers and patients by standardizing the clinical and therapeutic management to MCS patients; and (b) to improve and shed light on MCS misconceptions not supported by evidence-based medicine (EBM).

PET in patients with clear-cut multiple chemical sensitivity (MCS)

2002 ◽  
Vol 41 (06) ◽  
pp. 233-239 ◽  
Author(s):  
C. Hausteiner ◽  
A. Drzezga ◽  
P. Bartenstein ◽  
M. Schwaiger ◽  
H. Förstl ◽  
...  
Keyword(s):  
Single Photon ◽  
Photon Emission ◽  
Multiple Chemical Sensitivity ◽  
Environmental Chemicals ◽  
Chemical Sensitivity ◽  
Clear Cut ◽  
Positron Emission ◽  
Symptom Complex ◽  
Brain Changes ◽  
Multiple Chemical

SummaryAim: Multiple chemical sensitivity (MCS) is a controversially discussed symptom complex. Patients afflicted by MCS react to very low and generally nontoxic concentrations of environmental chemicals. It has been suggested that MCS leads to neurotoxic damage or neuroimmunological alteration in the brain detectable by positron emission tomography (PET) and single photon emission computer tomography (SPECT). These methods are often applied to MCS patients for diagnosis, although they never proved appropriate. Method: We scanned 12 MCS patients with PET, hypothesizing that it would reveal abnormal findings. Results: Mild glucose hypometabolism was present in one patient. In comparison with normal controls, the patient group showed no significant functional brain changes. Conclusion: This first systematic PET study in MCS patients revealed no hint of neurotoxic or neuroimmuno-logical brain changes of functional significance.

Multiple Chemical Sensitivity

2012 ◽  
Vol 24 (4) ◽  
pp. 328 ◽  
Author(s):  
Hong-Jae Chae ◽  
Byoung-Gwon Kim ◽  
Hwan-Cheol Kim ◽  
Mi-Young Lee ◽  
Jong-Han Leem
Keyword(s):  
Multiple Chemical Sensitivity ◽  
Chemical Sensitivity ◽  
Multiple Chemical

Patient Statement: A Canary's Tale

1994 ◽  
Vol 10 (4-5) ◽  
pp. 323-326
Author(s):  
Jacob Berkson
Keyword(s):  
Environmental Pollution ◽  
Multiple Chemical Sensitivity ◽  
Organophosphate Pesticide ◽  
Chemical Sensitivity ◽  
Environmental Illness ◽  
Trial Lawyer ◽  
Multiple Chemical

I am Jacob B. Berkson, a 68-year-old resident of Hagerstown, Maryland. I was a trial lawyer for some 40 years. I am now retired and writing a book on Environmental Pollution and Environmental Illness, titled A Canary's Tale. I was invited to speak to you as a patient one who was poisoned by an organophosphate pesticide and who subsequently developed Multiple Chemical Sensitivity (MCS, or sometimes referred to as Environmental Illness, EI).

Multiple chemical sensitivity: On the scent of central sensitization

2013 ◽  
Vol 216 (2) ◽  
pp. 202-210 ◽  
Author(s):  
Marie Thi Dao Tran ◽  
Lars Arendt-Nielsen ◽  
Ron Kupers ◽  
Jesper Elberling
Keyword(s):  
Central Sensitization ◽  
Multiple Chemical Sensitivity ◽  
Chemical Sensitivity ◽  
Multiple Chemical
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