Faculty Opinions recommendation of Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.

2012 ◽  
Author(s):  
Wolfgang Jahnke
Keyword(s):  
Antimalarial Activity ◽  
Geranylgeranyl Diphosphate Synthase ◽  
Geranylgeranyl Diphosphate

scholarly journals Distribution of prenyltransferases in rat tissues. Evidence for a cytosolic all-trans-geranylgeranyl diphosphate synthase.

1993 ◽  
Vol 268 (2) ◽  
pp. 832-838
Author(s):  
J. Ericsson ◽  
M. Runquist ◽  
A. Thelin ◽  
M. Andersson ◽  
T. Chojnacki ◽  
...  
Keyword(s):  
Rat Tissues ◽  
Geranylgeranyl Diphosphate Synthase ◽  
Geranylgeranyl Diphosphate

scholarly journals Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR Investigation

2009 ◽  
Vol 131 (14) ◽  
pp. 5153-5162 ◽  
Author(s):  
Yonghui Zhang ◽  
Rong Cao ◽  
Fenglin Yin ◽  
Michael P. Hudock ◽  
Rey-Ting Guo ◽  
...  
Keyword(s):  
Geranylgeranyl Diphosphate Synthase ◽  
Geranylgeranyl Diphosphate ◽  
X Ray

Studies on geranylgeranyl diphosphate synthase from rat liver: Specific inhibition by 3-azageranylgeranyl diphosphate

1992 ◽  
Vol 297 (2) ◽  
pp. 314-320 ◽  
Author(s):  
Hiroshi Sagami ◽  
Tatsumi Korenaga ◽  
Kyozo Ogura ◽  
Arthur Steiger ◽  
Hyung-Jung Pyun ◽  
...  
Keyword(s):  
Rat Liver ◽  
Specific Inhibition ◽  
Geranylgeranyl Diphosphate Synthase ◽  
Geranylgeranyl Diphosphate

scholarly journals Preclinical investigation of a potent geranylgeranyl diphosphate synthase inhibitor

2018 ◽  
Vol 36 (5) ◽  
pp. 810-818 ◽  
Author(s):  
Staci L. Haney ◽  
Yashpal S. Chhonker ◽  
Michelle L. Varney ◽  
Geoffrey Talmon ◽  
Daryl J. Murry ◽  
...  
Keyword(s):  
Geranylgeranyl Diphosphate Synthase ◽  
Geranylgeranyl Diphosphate ◽  
Preclinical Investigation ◽  
Synthase Inhibitor
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