Faculty Opinions recommendation of Allergen-specific oral immunotherapy for peanut allergy.

Author(s):  
John Routes ◽  
James Verbsky
2019 ◽  
Vol 40 (4) ◽  
pp. 214-220 ◽  
Author(s):  
Michael S. Blaiss ◽  
Stephen Tilles ◽  
Daniel Petroni ◽  
Ellen Zigmont ◽  
Marie Cassese ◽  
...  

2012 ◽  
Vol 129 (2) ◽  
pp. AB27 ◽  
Author(s):  
B.P. Vickery ◽  
P. Steele ◽  
J. Kamilaris ◽  
A. Edie ◽  
M. Kulis ◽  
...  

2012 ◽  
Vol 129 (2) ◽  
pp. AB140 ◽  
Author(s):  
S.J. Chin ◽  
E.H. Kim ◽  
M.D. Kulis ◽  
P. Varshney ◽  
P. Steele ◽  
...  

2018 ◽  
Vol 9 ◽  
Author(s):  
Benjamin L. Wright ◽  
Nielsen Q. Fernandez-Becker ◽  
Neeraja Kambham ◽  
Natasha Purington ◽  
Dana Tupa ◽  
...  

2015 ◽  
Vol 135 (2) ◽  
pp. AB235 ◽  
Author(s):  
Kamal D. Srivastava ◽  
Alyssa Siefert ◽  
Tarek Fahmy ◽  
Michael J. Caplan ◽  
Xiu-Min Li ◽  
...  

2018 ◽  
Vol 27 (6) ◽  
pp. 153-161 ◽  
Author(s):  
Wenming Zhang ◽  
Sayantani B. Sindher ◽  
Vanitha Sampath ◽  
Kari Nadeau

2020 ◽  
Vol 68 (6) ◽  
pp. 1152-1155
Author(s):  
Joan H Dunlop

The US Food and Drug Administration’s approval of a peanut oral immunotherapy product in January 2020 is a landmark development in the field of food allergy therapy. While food allergy prevalence has been increasing, this product is the first approved therapy for food allergy. Oral immunotherapy has many similarities to subcutaneous immunotherapy and drug desensitization protocols, but does not lead to sustained unresponsiveness. The studies leading to approval of the Palforzia product demonstrated increase in the amount of peanut protein able to be consumed, with 67% of subjects randomized to the treatment arm able to consume 600 mg of peanut protein in double-blind placebo-controlled food challenge at study exit. However, side effects are an important consideration, and dropout rates in studies of Palforzia ranged from 11% to 21%. Postmarketing surveillance of this product will be critical in assessing its long-term risks and benefits.


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