Faculty Opinions recommendation of What is the evidence base for atopic eczema treatments? A summary of published randomized controlled trials.

2016 ◽  
Author(s):  
Carsten Flohr ◽  
Teresa Tsakok
Keyword(s):  
Randomized Controlled Trials ◽  
Atopic Eczema ◽  
Evidence Base ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals What is the evidence base for atopic eczema treatments? A summary of published randomized controlled trials

2017 ◽  
Vol 176 (4) ◽  
pp. 910-927 ◽  
Author(s):  
H. Nankervis ◽  
K.S. Thomas ◽  
F.M. Delamere ◽  
S. Barbarot ◽  
S. Smith ◽  
...  
Keyword(s):  
Randomized Controlled Trials ◽  
Atopic Eczema ◽  
Evidence Base ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Are Randomized Controlled Trials Controlled? Patient Preferences and Unblind Trials

1997 ◽  
Vol 90 (12) ◽  
pp. 652-656 ◽  
Author(s):  
Klim Mcpherson ◽  
Annie R Britton ◽  
John E Wennberg
Keyword(s):  
Randomized Controlled Trials ◽  
Patient Preferences ◽  
Treatment Effects ◽  
Evidence Base ◽  
Modern Medicine ◽  
Treatment Preferences ◽  
Controlled Trials ◽  
True Nature ◽  
Randomized Controlled ◽  
Catch 22

The most reliable information about treatment effects comes from randomized controlled trials (RCTs). However, the possibility of subtle interactions—for example, between treatment preferences and treatment effects—is generally subordinated in the quest for evidence about main treatment effects. If patient preferences can influence the effectiveness of treatments through poorly understood (psychological) pathways, then RCTs, particularly when unblinded, may wrongly attribute effects solely to a treatment's physiological/pharmacological properties. To interpret the RCT evidence base it is important to know whether any preference effects exist and, if so, by how much they affect outcome. Reliable measurement of these effects is difficult and will require new approaches to the conduct of trials. In view of the fanciful image with which such effects are portrayed and the uncertainties about their true nature and biological mechanisms, existing evidence is unlikely to provide sufficient justification for investment in trials. This is a Catch 22. Until an escape is found we might never know, even approximately, how much of modern medicine is attributable to psychological processes.

scholarly journals Reporting of symptoms in randomized controlled trials of atopic eczema treatments: a systematic review

2016 ◽  
Vol 175 (4) ◽  
pp. 678-686 ◽  
Author(s):  
L.A.A. Gerbens ◽  
J.R. Chalmers ◽  
N.K. Rogers ◽  
H. Nankervis ◽  
P.I. Spuls ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Atopic Eczema ◽  
Controlled Trials ◽  
Randomized Controlled

The Clinical Effects of Red Blood Cell Transfusions: An Overview of the Randomized Controlled Trials Evidence Base

2011 ◽  
Vol 25 (2) ◽  
pp. 145-155.e2 ◽  
Author(s):  
Kirstin L. Wilkinson ◽  
Susan J. Brunskill ◽  
Carolyn Dorée ◽  
Sally Hopewell ◽  
Simon Stanworth ◽  
...  
Keyword(s):  
Blood Cell ◽  
Randomized Controlled Trials ◽  
Red Blood Cell ◽  
Evidence Base ◽  
Controlled Trials ◽  
Clinical Effects ◽  
Randomized Controlled ◽  
Red Blood Cell Transfusions

The Cochrane Skin Group: Promoting the Best Evidence

2005 ◽  
Vol 9 (6) ◽  
pp. 324-331
Author(s):  
Avanta Collier ◽  
Kathryn R. Johnson ◽  
Finola Delamere ◽  
Tina Leonard ◽  
Robert P. Dellavalle ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Randomized Controlled Trials ◽  
Systematic Reviews ◽  
Cochrane Collaboration ◽  
Evidence Base ◽  
Therapeutic Interventions ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
The Cochrane Collaboration ◽  
Evidence Summaries

Background: The international Cochrane Skin group, established in 1997, organizes, writes and disseminates systematic reviews of therapeutic interventions in dermatology. ObjectiveTo introduce the Cochrane Skin Group and what it offers to cutaneous medicine and surgery providers. Methods: Descriptive review of the structure and output of the Cochrane Collaboration Library and the Cochrane Skin Group. Results: Systematic reviews of randomized controlled trials produced through the Cochrane Skin Group provide a benchmark for evidence summaries for informing clinical decisions in dermatology. Conclusion: The work performed by the Cochrane Skin Group is an important component for informing the evidence base for the clinical practice of cutaneous and surgical dermatology.

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