Faculty Opinions recommendation of Reconciling evidence-based medicine and precision medicine in the era of big data: challenges and opportunities.

2016 ◽  
Author(s):  
Manuel Corpas
Keyword(s):  
Big Data ◽  
Precision Medicine ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
Challenges And Opportunities ◽  
Based Medicine

scholarly journals Application of Big Data Analytics with Evidence Based Medicine

2018 ◽  
Vol Volume-2 (Issue-4) ◽  
pp. 440-444
Author(s):  
Aravind G ◽  
Varun K ◽  
Manjunath C R | Soumya K N ◽  
Keyword(s):  
Big Data ◽  
Evidence Based Medicine ◽  
Data Analytics ◽  
Big Data Analytics ◽  
Evidence Based ◽  
Based Medicine

scholarly journals Mental disorders of known aetiology and precision medicine in psychiatry: a promising but neglected alliance

2016 ◽  
Vol 47 (2) ◽  
pp. 193-197 ◽  
Author(s):  
D. Fraguas ◽  
C. M. Díaz-Caneja ◽  
M. W. State ◽  
M. C. O'Donovan ◽  
R. E. Gur ◽  
...  
Keyword(s):  
Personalized Medicine ◽  
Mental Disorders ◽  
Precision Medicine ◽  
Psychiatric Disorders ◽  
Evidence Based Medicine ◽  
Prediction Models ◽  
Deletion Syndrome ◽  
Clinical Approach ◽  
Evidence Based ◽  
Based Medicine

Personalized or precision medicine is predicated on the assumption that the average response to treatment is not necessarily representative of the response of each individual. A commitment to personalized medicine demands an effort to bring evidence-based medicine and personalized medicine closer together. The use of relatively homogeneous groups, defined using a priori criteria, may constitute a promising initial step for developing more accurate risk-prediction models with which to advance the development of personalized evidence-based medicine approaches to heterogeneous syndromes such as schizophrenia. However, this can lead to a paradoxical situation in the field of psychiatry. Since there has been a tendency to loosely define psychiatric disorders as ones without a known aetiology, the discovery of an aetiology for psychiatric syndromes (e.g. 22q11.2 deletion syndrome in some cases of schizophrenia), while offering a path toward more precise treatments, may also lead to their reclassification away from psychiatry. We contend that psychiatric disorders with a known aetiology should not be removed from the field of psychiatry. This knowledge should be used instead to guide treatment, inasmuch as psychotherapies, pharmacotherapies and other treatments can all be valid approaches to mental disorders. The translation of the personalized clinical approach inherent to psychiatry into evidence-based precision medicine can lead to the development of novel treatment options for mental disorders and improve outcomes.

Large databases (Big Data) and evidence-based medicine

2018 ◽  
Vol 53 ◽  
pp. 1-2 ◽  
Author(s):  
Andrea Damiani ◽  
Graziano Onder ◽  
Vincenzo Valentini
Keyword(s):  
Big Data ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
Large Databases ◽  
Based Medicine

More Person-Centered?: The move from Evidence-Based Medicine to Precision Medicine

2020 ◽  
Vol 8 (2) ◽  
pp. 226
Author(s):  
Sarah Wieten
Keyword(s):  
Precision Medicine ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
Based Medicine

While a shift from Evidence-Based Medicine (EBM) to Precision Medicine has not yet taken place, I here argue that precision medicine has familiar problems with expertise, causes and values that we can see in Evidence-Based Medicine. Some of these similarities suggest we should be cautious in thinking of precision medicine as more person-centered than EBM.

scholarly journals Mistletoe - From mythology to evidence-based medicine

2015 ◽  
Vol 59 (4) ◽  
Author(s):  
Manuela Monti
Keyword(s):  
Precision Medicine ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
Private Company ◽  
State Of The Union ◽  
Precision Medicine Initiative ◽  
Based Medicine ◽  
Barak Obama

This is the time of the <em>precision medicine</em>, as President Barak Obama addressed the Nation on January 20, 2015 in a State of the Union Address: <em>Tonight, I'm launching a new Precision Medicine Initiative to bring us closer to curing diseases like cancer and diabetes — and to give all of us access to the personalized information we need to keep ourselves and our families healthier</em> (Francis S. Collins and Harold Varmus, A New Initiative on Precision Medicine; N Engl J Med 2015;372:793-795). This new field already show several actors, not only the NIH but also private company like APPLE, MICROSOFT and others, investing a lot of many: all together already several billions, dollars or euro doesn’t matter, a fact that testify how hot is becoming this new biomedical perspective....

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