Faculty Opinions recommendation of BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity.

2018 ◽  
Author(s):  
George Yap ◽  
Adeline Peignier
Keyword(s):  
Viral Infection ◽  
Bcg Vaccination ◽  
Trained Immunity ◽  
Experimental Viral Infection

scholarly journals BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

2018 ◽  
Vol 23 (1) ◽  
pp. 89-100.e5 ◽  
Author(s):  
Rob J.W. Arts ◽  
Simone J.C.F.M. Moorlag ◽  
Boris Novakovic ◽  
Yang Li ◽  
Shuang-Yin Wang ◽  
...  
Keyword(s):  
Viral Infection ◽  
Bcg Vaccination ◽  
Trained Immunity ◽  
Experimental Viral Infection

scholarly journals COVID-19: A model correlating BCG vaccination to protection from mortality implicates trained immunity

2020 ◽  
Author(s):  
Cameron M. Green ◽  
Stephanie Fanucchi ◽  
Jorge Dominguez-Andres ◽  
Ezio T. Fok ◽  
Simone J.C.F.M. Moorlag ◽  
...  
Keyword(s):  
Data Quality ◽  
List Type ◽  
Quality Model ◽  
Lethal Effects ◽  
Bcg Vaccination ◽  
Trained Immunity ◽  
Specific Effects

SummaryWe use a data quality model to demonstrate that BCG vaccination is correlated with protection from death from COVID19From a mechanistic perspective, BCG is well described to elicit its protective non-specific effects through the process of trained immunity.Therapeutically enhancing trained immunity may therefore be an important mechanism in protection from the lethal effects of COVID19

Effect of experimental viral infection in thymectomized rodents

1965 ◽  
Vol 31 (1) ◽  
pp. 145-152 ◽  
Author(s):  
R. Leyten ◽  
P. De Somer ◽  
P. Denys ◽  
A. Prinzie
Keyword(s):  
Viral Infection ◽  
Experimental Viral Infection

scholarly journals THE INFLUENCE OF CORTISONE ON EXPERIMENTAL VIRAL INFECTION

1966 ◽  
Vol 123 (5) ◽  
pp. 767-775 ◽  
Author(s):  
Michael W. Rytel ◽  
Edwin D. Kilbourne
Keyword(s):  
Viral Infection ◽  
Intravenous Injection ◽  
Marked Reduction ◽  
Interferon Response ◽  
Experimental Viral Infection

The administration, of 5.0 mg of cortisone 6 to 24 hr prior to the intravenous injection of mice with NDV was associated with a marked reduction in the interferon response as measured in serum and spleen. Reduced concentrations of interferon following cortisone pretreatment were demonstrable from 6 to 16 hr following injection of virus.

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