scholarly journals Steroid Therapy in Branch Retinal Vein Occlusion and Macular Edema

Macular edema is the most common cause of vision loss in branch retinal vein occlusion. Mechanism of macular edema in branch retinal vein occlusion is multifactorial and it has not yet been fully understood. With the new information obtained from the new studies, treatment modalities have been changed. Nowadays besides laser and intravitreal triamcinolone acetonide treatments, intravitreal antivascular endothelial growth factor and dexamethasone implant therapies are commonly used. In this review, we aimed to evaluate the intravitreal steroid treatment in branch retinal vein occlusion.

Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins

The Standard Care vs. Corticosteroid for Retinal Vein Occlusion (SCORE-CRVO) Study was a randomized clinical trial comparing intravitreal triamcinolone to observation in eyes with vision loss associated with macular edema due to perfused (nonischemic) central retinal vein occlusion (CRVO). The results suggested that intravitreal triamcinolone in a 1-mg dose should be considered for up to 1 year, and possibly 2 years, in patients with vision loss associated with macular edema secondary to CRVO. The study was the first to establish an effective treatment for perfused CRVO. (Treatment with intravitreal anti–vascular endothelial growth factor [VEGF] agents has been shown to produce greater improvement in visual acuity and is now the standard of care.)


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