What We Have Learned About Corneal Wound Healing From Refractive Surgery

1989 ◽  
Vol 5 (2) ◽  
pp. 98-99 ◽  
Author(s):  
Perry S Binder
2009 ◽  
Vol 03 (02) ◽  
pp. 64
Author(s):  
Irene C Kuo ◽  

Research into corneal wound healing is gaining renewed interest with the increasing volume of keratorefractive procedures. Such research may help avoid the complication of ectasia after laser refractive surgery. There are three histopathological types of wound healing after keratorefractive surgery – whether laser refractive surgery, penetrating keratoplasty or radial keratotomy – and these are reviewed in this paper. They are hypercellular fibrotic stromal scar preceded by activated keratocytes, epithelial hyperplasia or hypertrophy and hypocellular primitive stromal scar. All can be identified with light, electron and immunofluorescence microscopy (or, with less detail, by confocal microscopy). A single procedure can manifest all three types of wound healing. Tissue destruction is part of tissue remodelling, but in successful procedures destruction cannot be uncontrolled or excessive. The elucidation of the signalling components remains an important area of research.


1963 ◽  
Vol 56 (5) ◽  
pp. 833-834
Author(s):  
N.A. Wine ◽  
P.K. Basu

2011 ◽  
Vol 52 (9) ◽  
pp. 6213 ◽  
Author(s):  
Andri K. Riau ◽  
Romesh I. Angunawela ◽  
Shyam S. Chaurasia ◽  
Wing S. Lee ◽  
Donald T. Tan ◽  
...  

2018 ◽  
Vol 192 ◽  
pp. 240-250 ◽  
Author(s):  
Wenhua Xu ◽  
Zheying Wang ◽  
Ying Liu ◽  
Liping Wang ◽  
Zhiwen Jiang ◽  
...  

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