scholarly journals Effect of dietary phosphate intake on the circadian rhythm of serum phosphate concentrations in chronic kidney disease: a crossover study

2014 ◽  
Vol 100 (5) ◽  
pp. 1392-1397 ◽  
Author(s):  
Joachim H Ix ◽  
Cheryl AM Anderson ◽  
Gerard Smits ◽  
Martha S Persky ◽  
Geoffrey A Block
Author(s):  
Marguerite Conley ◽  
Katrina L. Campbell ◽  
Carmel M. Hawley ◽  
Nicole M. Lioufas ◽  
Grahame J. Elder ◽  
...  

2012 ◽  
Vol 28 (1) ◽  
pp. 161-169 ◽  
Author(s):  
Mhairi Sigrist ◽  
Mila Tang ◽  
Monica Beaulieu ◽  
Gabriella Espino-Hernandez ◽  
Lee Er ◽  
...  

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii590-iii590
Author(s):  
Almirall Jaume ◽  
Betancourt Loreley ◽  
Martinez-Ocaña Juan Carlos ◽  
Ponz Esther ◽  
Luengo Marina ◽  
...  

2019 ◽  
pp. 2-3

Impaired phosphate excretion by the kidney leads to Hyperphosphatemia. It is an independent predictor of cardiovascular disease and mortality in patients with advanced chronic kidney disease (stage 4 and 5) particularly in case of dialysis. Phosphate retention develops early in chronic kidney disease (CKD) due to the reduction in the filtered phosphate load. Overt hyperphosphatemia develops when the estimated glomerular filtration rate (eGFR) falls below 25 to 40 mL/min/1.73 m2. Hyperphosphatemia is typically managed with oral phosphate binders in conjunction with dietary phosphate restriction. These drugs aim to decrease serum phosphate by binding ingested phosphorus in the gastrointestinal tract and its transformation to non-absorbable complexes [1].


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