Rapidly Progressive Interstitial Lung Disease Associated with Dermatomyositis; A Case Report

2007 ◽  
Vol 14 (4) ◽  
pp. 401
Author(s):  
Jae Young Yoon ◽  
Sun Yang Min ◽  
Ju Yee Park ◽  
Seung Goun Hong ◽  
Hyo Jong Kang
2019 ◽  
Vol 26 (5) ◽  
pp. 1241-1243 ◽  
Author(s):  
Sarah Howlett ◽  
Raminder Aul ◽  
Mark Hill ◽  
David J Pinato

Introduction Raltitrexed is a folate analogue, which selectively inhibits thymidylate synthase, used in the treatment of colorectal carcinoma. Common side effects include asthenia and gastrointestinal and haematological toxicities. Case report We present the case of a 74-year-old gentleman with incidental mild interstitial lung disease on preoperative staging CT Chest who developed acute breathlessness whilst undergoing adjuvant raltitrexed treatment for a completely excised colorectal adenocarcinoma. Management and outcome Discontinuation of raltitrexed and a course of steroid therapy resulted in resolution of symptoms, mirrored by an improvement in lung function tests. Discussion The clinical pattern of rapid progression with steroid response highlights the potential for significant acceleration of interstitial lung disease by raltitrexed.


Pharmacology ◽  
2011 ◽  
Vol 87 (5-6) ◽  
pp. 318-320 ◽  
Author(s):  
Aymen Zayen ◽  
Henda Rais ◽  
Hela Rifi ◽  
Mouna Ouarda ◽  
Mehdi Afrit ◽  
...  

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Tetsuya Suzuki ◽  
Yukiko Shimoda ◽  
Katsuji Teruya ◽  
Hiroyuki Gatanaga ◽  
Yoshimi Kikuchi ◽  
...  

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