scholarly journals Clear-cell variant urothelial carcinoma of the bladder: a case report and review of the literature

Rare Tumors ◽  
2012 ◽  
Vol 4 (4) ◽  
pp. 153-155 ◽  
Author(s):  
Mario W. Kramer ◽  
Mahmoud Abbas ◽  
Stefanie Pertschy ◽  
Jan Ulrich Becker ◽  
Hans-Heinrich Kreipe ◽  
...  

Clear cell variants of transitional cell carcinomas (TCC) of the bladder are extremely rare tumors. Only 6 cases have been reported until now. We report of a 67 year old man who presented with fast growing tumor disease. While initial diagnosis showed localized bladder tumor, final histopathology revealed pT4, G3, L1 urothelial carcinoma with clear cell differentiation. No more than 14 weeks after initial diagnosis the patient died from multi-organ failure after unsuccessful salvage laparotomy which showed massive tumor burden within the pelvis and peritoneal carcinosis. This case demonstrated an extremely fast tumor growth. Therefore, patients with clear cell urothelial carcinoma should be treated vigorously and without time delay. We present a case of clear cell variant of TCC which exhibited an extremely aggressive behavior. To our knowledge this is the fifth report of this rare disease.

Author(s):  
Ioana Mihai ◽  
Sorina Taban ◽  
Alin Cumpanas ◽  
Emilian Gh. Olteanu ◽  
Mihaela Iacob ◽  
...  

The most common histological type of urinary bladder cancer is urothelial carcinoma (UC). In contrast, the clear cell variant of urothelial carcinoma (CCUC) is quite a rare neoplasm. In this study, we report a case of an 81-year-old male, presenting with gross hematuria and acute urinary retention, which was subsequently diagnosed with CCUC at our pathology department. Furthermore, we provide a short systematic review of the literature (PubMed, Scopus, Science Citation Index) for this rare histopathological entity and a brief discussion about its morphological and immunohistochemical (IHC) characteristics.


2006 ◽  
Vol 13 (11) ◽  
pp. 1448-1450 ◽  
Author(s):  
RYO YAMASHITA ◽  
RAIZOU YAMAGUCHI ◽  
KEIJI YUEN ◽  
MASASHI NIWAKAWA ◽  
KENICHI TOBISU

Head & Neck ◽  
1994 ◽  
Vol 16 (3) ◽  
pp. 272-277 ◽  
Author(s):  
M. John Hicks ◽  
Catherine M. Flaitz ◽  
Mark E. K. Wong ◽  
R. Keith McDaniel ◽  
Philip T. Cagle

2020 ◽  
Vol 33 ◽  
pp. 101331
Author(s):  
Anuj Mahajan ◽  
Prashanth Adiga ◽  
Aaron Fernandes

2019 ◽  
Vol 27 (5) ◽  
pp. 535-540
Author(s):  
Cristina Costales ◽  
Arjun Mehta ◽  
Sujit Kulkarni ◽  
Brent K. Larson

The clear cell variant of solid pseudopapillary neoplasm (ccSPN) of the pancreas was first described in 2006. In this article, we report a case of this rare variant and review the few published reports. Both the current and previous reports show that ccSPN has several morphologic differences from conventional SPN, including clear vacuoles, fewer pseudopapillary formations, more solid/diffuse architecture, less hemorrhage, and fewer cholesterol clefts. Some of these features peculiar to ccSPN, such as solid/diffuse architecture, have been proposed to suggest aggressive behavior, though reports of ccSPN are rare and often have limited clinical follow-up. ccSPN also appears to occur more frequently in males than conventional SPNs. These clinical and pathologic features lead to unique set of differential diagnostic considerations for ccSPN, including metastatic renal cell carcinoma, perivascular epithelial cell tumor, and clear cell variants of other carcinomas. These unique features, atypical differential, and uncertain prognostic ramifications all make ccSPN an important variant to be aware of and report.


2012 ◽  
Vol 6 (6) ◽  
pp. 431 ◽  
Author(s):  
Victor A. McPherson ◽  
Michael Ott ◽  
Edward J. Tweedie ◽  
Jonathan Izawa

The overall 5-year survival of patients with urothelial carcinoma of the bladder (UC) is about 78%; however, there are some rare subtypes. One of these is the lipoid cell subtype, which bears a very poor prognosis. Another rare disease entity with a poor prognosis is metastasis to the lower gastrointestinal tract in the form of secondary linitis plastica of the rectum. We describe an extremely rare and unique case of rectal linitis plastica secondary to the rare lipoid cell variant of UC.


2012 ◽  
Vol 84 (3) ◽  
pp. 191-194 ◽  
Author(s):  
T. Klimis ◽  
G. P. Dellaportas

2001 ◽  
Vol 80 (3) ◽  
pp. 409-412 ◽  
Author(s):  
Mitsuko Furuya ◽  
Michio Shimizu ◽  
Hiroshi Nishihara ◽  
Tomoo Ito ◽  
Noriaki Sakuragi ◽  
...  

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