Role of Functional Neuroimaging in Primary Headache Disorders

2021 ◽  
Vol 69 (7) ◽  
pp. 10
Author(s):  
Steffen Naegel ◽  
Mark Obermann
Cephalalgia ◽  
2018 ◽  
Vol 39 (13) ◽  
pp. 1635-1660 ◽  
Author(s):  
Marta Vila-Pueyo ◽  
Jan Hoffmann ◽  
Marcela Romero-Reyes ◽  
Simon Akerman

Objective To review and discuss the literature relevant to the role of brainstem structure and function in headache. Background Primary headache disorders, such as migraine and cluster headache, are considered disorders of the brain. As well as head-related pain, these headache disorders are also associated with other neurological symptoms, such as those related to sensory, homeostatic, autonomic, cognitive and affective processing that can all occur before, during or even after headache has ceased. Many imaging studies demonstrate activation in brainstem areas that appear specifically associated with headache disorders, especially migraine, which may be related to the mechanisms of many of these symptoms. This is further supported by preclinical studies, which demonstrate that modulation of specific brainstem nuclei alters sensory processing relevant to these symptoms, including headache, cranial autonomic responses and homeostatic mechanisms. Review focus This review will specifically focus on the role of brainstem structures relevant to primary headaches, including medullary, pontine, and midbrain, and describe their functional role and how they relate to mechanisms of primary headaches, especially migraine.


2007 ◽  
Vol 65 (3b) ◽  
pp. 852-854 ◽  
Author(s):  
Guilherme Gustavo Riccioppo Rodrigues ◽  
Carlos Alberto Bordini ◽  
Fabíola Dach ◽  
Alan Eckeli ◽  
José Geraldo Speciali

SUNCT is one of the rarest and least known primary headache disorders. Although its pathogenesis has been partially understood by functional neuroimaging and reports of secondary cases, there is limited understanding of its cause. We report a case of SUNCT in a 54-years-old man, that could not be strictly classified as secondary SUNCT; however, the time lag of pain onset suggests a new theory in which neuroplasticity could be involved in the origin and duration of the pain in SUNCT syndrome.


2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Jasem Y. Al-Hashel ◽  
Samar Farouk Ahmed ◽  
Fatemah J Alshawaf ◽  
Raed Alroughani

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