Phenylbutazone-induced generalized bullous fixed drug eruption masquerading Stevens-Johnson syndrome/toxic epidermal necrolysis

Author(s):  
HariKishan Kumar Yadalla ◽  
AnaghaRamesh Babu
2013 ◽  
Vol 168 (4) ◽  
pp. 726-732 ◽  
Author(s):  
S. Lipowicz ◽  
P. Sekula ◽  
S. Ingen-Housz-Oro ◽  
Y. Liss ◽  
B. Sassolas ◽  
...  

Medicina ◽  
2021 ◽  
Vol 57 (9) ◽  
pp. 925
Author(s):  
Hannah J. Anderson ◽  
Jason B. Lee

Fixed drug eruption (FDE) is a cutaneous adverse drug reaction characterized by the onset of rash at a fixed location on the body each time a specific medication is ingested. With each recurrence, the eruption can involve additional sites. Lesions can have overlying vesicles and/or bullae, and when they cover a significant percentage of body surface area, the eruption is referred to as generalized bullous fixed drug eruption (GBFDE). Due to the widespread skin denudation that can be seen in this condition, GBFDE may be confused clinically with Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). While treatments described for GBFDE include supportive care, topical and/or systemic steroids, and, recently, cyclosporine, the mainstay of management involves identifying and discontinuing the causative drug. This review article will provide an overview of FDE with an emphasis on its generalized bullous variant.


2019 ◽  
Vol 32 (4) ◽  
pp. 601-602
Author(s):  
Meredith Gavin ◽  
Leigha Sharp ◽  
Kendra Walker ◽  
Emily Behrens ◽  
Russell Akin ◽  
...  

2015 ◽  
Vol 48 (5) ◽  
pp. 551-554 ◽  
Author(s):  
Farid M. Dharamsi ◽  
Michael D. Michener ◽  
Jennifer Warner Dharamsi

2018 ◽  
Vol 2 (1) ◽  
pp. 34
Author(s):  
BanavasiShanmukha Girisha ◽  
TonitaMariola Noronha ◽  
AkshataCharan Alva ◽  
Ashok Menon

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