Bullous fixed drug eruption mimicking Stevens–Johnson Syndrome

2014 ◽  
Vol 70 (5) ◽  
pp. AB39 ◽  
Keyword(s):  
Drug Eruption ◽  
Stevens Johnson Syndrome ◽  
Fixed Drug Eruption ◽  
Johnson Syndrome ◽  
Fixed Drug

Prognosis of generalized bullous fixed drug eruption: comparison with Stevens-Johnson syndrome and toxic epidermal necrolysis

2013 ◽  
Vol 168 (4) ◽  
pp. 726-732 ◽  
Author(s):  
S. Lipowicz ◽  
P. Sekula ◽  
S. Ingen-Housz-Oro ◽  
Y. Liss ◽  
B. Sassolas ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Drug Eruption ◽  
Stevens Johnson Syndrome ◽  
Fixed Drug Eruption ◽  
Johnson Syndrome ◽  
Fixed Drug

scholarly journals A Review of Fixed Drug Eruption with a Special Focus on Generalized Bullous Fixed Drug Eruption

Medicina ◽  
2021 ◽  
Vol 57 (9) ◽  
pp. 925
Author(s):  
Hannah J. Anderson ◽  
Jason B. Lee
Keyword(s):  
Drug Eruption ◽  
The Body ◽  
Stevens Johnson Syndrome ◽  
Special Focus ◽  
Fixed Drug Eruption ◽  
Causative Drug ◽  
Johnson Syndrome ◽  
Fixed Drug ◽  
Specific Medication ◽  
Cutaneous Adverse Drug Reaction

Fixed drug eruption (FDE) is a cutaneous adverse drug reaction characterized by the onset of rash at a fixed location on the body each time a specific medication is ingested. With each recurrence, the eruption can involve additional sites. Lesions can have overlying vesicles and/or bullae, and when they cover a significant percentage of body surface area, the eruption is referred to as generalized bullous fixed drug eruption (GBFDE). Due to the widespread skin denudation that can be seen in this condition, GBFDE may be confused clinically with Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). While treatments described for GBFDE include supportive care, topical and/or systemic steroids, and, recently, cyclosporine, the mainstay of management involves identifying and discontinuing the causative drug. This review article will provide an overview of FDE with an emphasis on its generalized bullous variant.

scholarly journals Contrast-induced generalized bullous fixed drug eruption resembling Stevens-Johnson syndrome

2019 ◽  
Vol 32 (4) ◽  
pp. 601-602
Author(s):  
Meredith Gavin ◽  
Leigha Sharp ◽  
Kendra Walker ◽  
Emily Behrens ◽  
Russell Akin ◽  
...  
Keyword(s):  
Drug Eruption ◽  
Stevens Johnson Syndrome ◽  
Fixed Drug Eruption ◽  
Johnson Syndrome ◽  
Fixed Drug

Bullous Fixed Drug Eruption Masquerading as Recurrent Stevens Johnson Syndrome

2015 ◽  
Vol 48 (5) ◽  
pp. 551-554 ◽  
Author(s):  
Farid M. Dharamsi ◽  
Michael D. Michener ◽  
Jennifer Warner Dharamsi
Keyword(s):  
Drug Eruption ◽  
Stevens Johnson Syndrome ◽  
Fixed Drug Eruption ◽  
Johnson Syndrome ◽  
Fixed Drug

Missed Diagnosis of Epilepsy-Associated Scald Burns: Two Cases Initially Diagnosed as Bullous Dermatosis

2020 ◽  
Author(s):  
Laura Giraud-Kerleroux ◽  
Chloé Charpentier ◽  
Charlotte Bernigaud ◽  
Nicolas Ortonne ◽  
Camille Hua ◽  
...  
Keyword(s):  
Adverse Reactions ◽  
Stevens Johnson Syndrome ◽  
Fixed Drug Eruption ◽  
Antiepileptic Treatment ◽  
Bullous Dermatosis ◽  
Johnson Syndrome ◽  
Fixed Drug ◽  
Epileptic Attack ◽  
Missed Diagnosis ◽  
Cutaneous Adverse Reactions

Abstract Thermal burns can occur during seizure. This diagnosis can be difficult in case of atypical lesions, even more if the epilepsy is unknown and in case of seizures with loss of consciousness and/or an unwitnessed epileptic attack. We report two cases of cutaneous bullous lesions initially misdiagnosed as severe acute cutaneous adverse reactions (generalized bullous fixed drug eruption and Stevens–Johnson syndrome). In the two cases, the clinical aspect, necrotic evolution, and absence of obvious attributable medication allowed to revert to the diagnosis of burns due to boiling water revealing previously unknown epilepsy. For both, surgical management with skin graft was performed, and antiepileptic treatment was introduced. Facing unexplained burns, occult epilepsy should be investigated. Questioning of patient and relatives is crucial.

Sign in / Sign up

Export Citation Format

Share Document