scholarly journals Malignant peripheral nerve sheath tumor arising from plexiform neurofibroma of the mesentery in a patient with neurofibromatosis 1

2015 ◽  
Vol 4 (1) ◽  
pp. 58
Author(s):  
Karuna Kumar ◽  
Ganthimathy Sekhar ◽  
Chitra Srinivasan ◽  
Jayaganesh Parthasarathy
Keyword(s):  
Peripheral Nerve ◽  
Plexiform Neurofibroma ◽  
Neurofibromatosis 1 ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

scholarly journals Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells

Oncotarget ◽  
2016 ◽  
Vol 7 (24) ◽  
pp. 35753-35767 ◽  
Author(s):  
Jennifer Varin ◽  
Laury Poulain ◽  
Mikael Hivelin ◽  
Patrick Nusbaum ◽  
Arnaud Hubas ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Tumor Cells ◽  
Plexiform Neurofibroma ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Proliferative Effect ◽  
Nerve Sheath

scholarly journals Malignant peripheral nerve sheath tumor in a patient with neurofibromatosis 1

2007 ◽  
Vol 13 (1) ◽  
pp. 104-107 ◽  
Author(s):  
Takahiro Segawa ◽  
Masahiko Kanamori ◽  
Taketoshi Yasuda ◽  
Shigeharu Nogami ◽  
Kayo Suzuki ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Neurofibromatosis 1 ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

scholarly journals Neurofibromatosis 1 associated to malignant peripheral nerve sheath tumor: A radiological approach

2020 ◽  
Vol 53 (2) ◽  
pp. 157-164
Author(s):  
Edgar Martínez Barrios ◽  
Léia Bortolatto ◽  
Ernesto Martínez Bogado ◽  
Oscar Gustavo Noguera
Keyword(s):  
Peripheral Nerve ◽  
Neurofibromatosis 1 ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Glandular Malignant Peripheral Nerve Sheath Tumor

2000 ◽  
Vol 124 (9) ◽  
pp. 1364-1368 ◽  
Author(s):  
Tetsuro Nagasaka ◽  
Raymond Lai ◽  
Michihiko Sone ◽  
Tsutomu Nakashima ◽  
Nobuo Nakashima
Keyword(s):  
Peripheral Nerve ◽  
Plexiform Neurofibroma ◽  
Neck Mass ◽  
Nerve Trunk ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Spindle Cells ◽  
Glandular Structures ◽  
Mitotic Figures

Abstract In this report, we describe a highly unusual case of glandular malignant peripheral nerve sheath tumor presenting as a neck mass in a previously healthy 29-year-old man. Grossly, the tumor was found to arise from a swollen peripheral nerve trunk. The tumor was largely composed of spindle cells that demonstrated marked nuclear pleomorphism and numerous abnormal mitotic figures. In addition, histologically malignant glandular structures lined by simple nonciliated columnar cells with goblet cells were found clustered in the center of the tumor. Examination of the swollen peripheral nerve trunk revealed the presence of a plexiform neurofibroma. The spindle cells were positive for S100. The glands were negative for S100 but positive for keratin, epithelial membrane antigen, and neuroendocrine markers (somatostatin, chromogranin, Leu-7, and calcitonin). This patient was subsequently diagnosed as having von Recklinghausen disease and died of tumor metastasis to the lungs 34 months after the presentation. To our knowledge, only 3 similar cases have been previously described in the literature.

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