Improving the downstream processing of vaccine and gene therapy vectors with continuous chromatography

2015 ◽  
Vol 3 (8) ◽  
pp. 489-505 ◽  
Author(s):  
Ricardo JS Silva ◽  
José PB Mota ◽  
Cristina Peixoto ◽  
Paula M Alves ◽  
Manuel JT Carrondo
Keyword(s):  
Gene Therapy ◽  
Downstream Processing ◽  
Continuous Chromatography ◽  
Gene Therapy Vectors

Downstream processing of oncoretroviral and lentiviral gene therapy vectors

2006 ◽  
Vol 24 (3) ◽  
pp. 321-337 ◽  
Author(s):  
María de las Mercedes Segura ◽  
Amine Kamen ◽  
Alain Garnier
Keyword(s):  
Gene Therapy ◽  
Downstream Processing ◽  
Gene Therapy Vectors ◽  
Lentiviral Gene Therapy

scholarly journals Quantitation of Trace Levels of DNA Released from Disrupted Adeno-Associated Virus Gene Therapy Vectors

2021 ◽  
Author(s):  
Jared S. Bee ◽  
Kristin O'Berry ◽  
Yu (Zoe) Zhang ◽  
Megan Kuhn Phillippi ◽  
Akanksha Kaushal ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Adeno Associated Virus ◽  
Virus Gene ◽  
Gene Therapy Vectors

A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography

2005 ◽  
Vol 90 (4) ◽  
pp. 391-404 ◽  
Author(s):  
Mar�a de las Mercedes Segura ◽  
Amine Kamen ◽  
Pierre Trudel ◽  
Alain Garnier
Keyword(s):  
Gene Therapy ◽  
Affinity Chromatography ◽  
Gene Therapy Vectors ◽  
Heparin Affinity

scholarly journals Recognition of Virus Infection and Innate Host Responses to Viral Gene Therapy Vectors

2010 ◽  
Vol 18 (8) ◽  
pp. 1422-1429 ◽  
Author(s):  
Dmitry M Shayakhmetov ◽  
Nelson C Di Paolo ◽  
Karen L Mossman
Keyword(s):  
Gene Therapy ◽  
Virus Infection ◽  
Host Responses ◽  
Viral Gene ◽  
Viral Gene Therapy ◽  
Gene Therapy Vectors

In Vivo Potency Assay for Adeno-Associated Virus–Based Gene Therapy Vectors Using AAVrh.10 as an Example

2018 ◽  
Vol 29 (3) ◽  
pp. 146-155 ◽  
Author(s):  
Bishnu P. De ◽  
Alvin Chen ◽  
Christiana O. Salami ◽  
Benjamin Van de Graaf ◽  
Jonathan B. Rosenberg ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Potency Assay ◽  
Adeno Associated Virus ◽  
Gene Therapy Vectors
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