scholarly journals Metabolic Studies of Amino Acids by Rat Liver Cells in Primary Culture

1978 ◽  
Vol 31 (6) ◽  
pp. 571-577
Author(s):  
Kyoichi KISHI ◽  
Yoshiaki FUJITA ◽  
Keiji TANAKA ◽  
Akira ICHIHARA
1975 ◽  
Vol 146 (2) ◽  
pp. 457-464 ◽  
Author(s):  
J M Mourão ◽  
J D McGivan ◽  
J B Chappell

With either alanine or a mixture of 15 different amino acids as nitrogen source, the addition of L-leucine inhibited the synthesis of urea by isolated rat liver cells. With alanine present leucine promoted the production of glutamate and glutamine. Comparison of effects of leucine on soluble glutamate dehydrogenase, mitochondria and isolated cells supports the postulate that leucine exerts its effect through activation of glutamate dehydrogenase. It is suggested that this latter enzyme may not be as important for the production of NH3 for carbamoyl phosphate synthesis as has been considered hitherto.


Lipids ◽  
1971 ◽  
Vol 6 (8) ◽  
pp. 601-608 ◽  
Author(s):  
David M. Capuzzi ◽  
Simeon Margolis

1985 ◽  
Vol 13 (4) ◽  
pp. 693-694
Author(s):  
MARK SALTER ◽  
RICHARD G. KNOWLES ◽  
CHRISTOPHER I. POGSON

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