Rehabilitation Medicine Implications of Stem Cell Therapy in Spinal Cord Injury–A Review

2013 ◽  
Vol 24 (1) ◽  
pp. 9-15
Author(s):  
U Singh ◽  
Gita Handa ◽  
K B Sumalatha

Abstract The life expectancy in spinal cord injury has increased but no cure has been found yet. Stem cell therapy in the spinal cord injury stands high hopes of neural repair and regeneration and getting back to normal life. But for its fruitful result it is essential to know the pathophysiology of the spinal cord injury and also the treatment should be appropriately timed according to the stages of injury. Regular follow-up of these patients is very important as stem cell therapy alone without appropriate rehabilitation may not only result in failure of therapy but also patients may end up in complications such as UTI, bed sores etc. Role of rehab in spinal cord injury with respect to physiological and task oriented neuroplasticity has shown benefits in animal studies. Rehabilitation programme integrated with the stem cell therapy may help to improve the functional outcome.

2019 ◽  
Vol 32 (3) ◽  
pp. 308-316 ◽  
Author(s):  
Ömercan Albayrak ◽  
Tarık Emre Şener ◽  
Mehmet Erşahin ◽  
Suna Özbaş-Turan ◽  
Ceyda Ekentok ◽  
...  

2011 ◽  
Vol 3 (1) ◽  
pp. 100-106
Author(s):  
Hala Gabr ◽  
Osama Ghannam ◽  
Mohamed Reda Awad ◽  
Klaus von Wild ◽  
Wael Abo El-Kheir ◽  
...  

2008 ◽  
Vol 5 (1) ◽  
pp. 7-10
Author(s):  
Khalil Isaac Mathai ◽  
Sasivadanan ◽  
S Sudumbraker ◽  
PK Sahoo

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Fahuan Song ◽  
Mei Tian ◽  
Hong Zhang

Spinal cord injury (SCI) is a serious disease of the center nervous system (CNS). It is a devastating injury with sudden loss of motor, sensory, and autonomic function distal to the level of trauma and produces great personal and societal costs. Currently, there are no remarkable effective therapies for the treatment of SCI. Compared to traditional treatment methods, stem cell transplantation therapy holds potential for repair and functional plasticity after SCI. However, the mechanism of stem cell therapy for SCI remains largely unknown and obscure partly due to the lack of efficient stem cell trafficking methods. Molecular imaging technology including positron emission tomography (PET), magnetic resonance imaging (MRI), optical imaging (i.e., bioluminescence imaging (BLI)) gives the hope to complete the knowledge concerning basic stem cell biology survival, migration, differentiation, and integration in real time when transplanted into damaged spinal cord. In this paper, we mainly review the molecular imaging technology in stem cell therapy for SCI.


2012 ◽  
Vol 8 (3) ◽  
pp. 953-962 ◽  
Author(s):  
Mevci Ozdemir ◽  
Ayhan Attar ◽  
Isinsu Kuzu ◽  
Murat Ayten ◽  
Enver Ozgencil ◽  
...  

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