Adjacent Corticocancellous Bone Graft in Anterior Cervical Interbody Fusion: A Technical Note

This study aimed to explore the safety and efficacy of using nano-hydroxyapatite/polyamide (N-HA/PA) composite in anterior cervical vertebral body subtotal corpectomy and interbody fusion. Total 50 patients with cervical spondylotic myelopathy were enrolled to undergo anterior cervical spondylectomy. Bone graft pedicles were compounded with N-HA/PA and intervertebral body fusion was performed. Study outcomes included surgical efficacy and the degree of fusion. Patients in whom vertebral body fusion was performed with N-HA/PA composite pedicles had significantly improved symptoms. The postoperative Japanese Orthopaedic Association scores increased to 18.56±4.37 from 11.37±3.52, reflecting an improvement rate of 87.3%. The composite pedicle fusion rate was 96.4%. Therefore, N-HA/PA composite pedicle as a bone graft material in fusion surgery provides significant therapeutic efficacy. Moreover, the composite pedicle fusion rate is high, making it ideal for anterior cervical vertebral body subtotal corpectomy and fusion.

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Obtention of injectable platelets rich-fibrin (i-PRF) and its polymerization with bone graft: technical note

Revista do Colégio Brasileiro de Cirurgiões ◽

10.1590/0100-69912015006013 ◽

2015 ◽

Vol 42 (6) ◽

pp. 421-423 ◽

Cited By ~ 27

Author(s):

Carlos Fernando de Almeida Barros Mourão ◽

Helder Valiense ◽

Elias Rodrigues Melo ◽

Natália Belmock Mascarenhas Freitas Mourão ◽

Mônica Diuana-Calasans Maia

Keyword(s):

Bone Graft ◽

Platelet Rich Plasma ◽

Technical Note ◽

Platelet Concentrates ◽

Soft Tissue Healing ◽

Liquid Form ◽

Platelet Rich Fibrin ◽

Tissue Healing ◽

Autologous Platelet ◽

Injectable Form

The use of autologous platelet concentrates, represent a promising and innovator tools in the medicine and dentistry today. The goal is to accelerate hard and soft tissue healing. Among them, the platelet-rich plasma (PRP) is the main alternative for use in liquid form (injectable). These injectable form ofplatelet concentrates are often used in regenerative procedures and demonstrate good results. The aim of this study is to present an alternative to these platelet concentrates using the platelet-rich fibrin in liquid form (injectable) and its use with particulated bone graft materials in the polymerized form.

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Difference of Fusion Rate in Minimally Invasive Transforaminal Lumbar Interbody Fusion with Autobone and Hydroxyapatite according to Mixture Ratio and Amount of Bone Graft

The Journal of the Korean Orthopaedic Association ◽

10.4055/jkoa.2013.48.5.382 ◽

2013 ◽

Vol 48 (5) ◽

pp. 382

Author(s):

Jae-Sung Yoo ◽

Sang-Hyuk Min ◽

Sung-Hyun Yoon ◽

Jun-Yeul Lee

Keyword(s):

Minimally Invasive ◽

Bone Graft ◽

Interbody Fusion ◽

Transforaminal Lumbar Interbody Fusion ◽

Fusion Rate ◽

Lumbar Interbody Fusion ◽

Mixture Ratio

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Hydroxyapatite/collagen composite graft for posterior lumbar interbody fusion: a comparison with local bone graft

Journal of Orthopaedic Surgery and Research ◽

10.1186/s13018-021-02798-4 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Toshitaka Yoshii ◽

Motonori Hashimoto ◽

Satoru Egawa ◽

Takashi Hirai ◽

Hiroyuki Inose ◽

...

Keyword(s):

Bone Graft ◽

Interbody Fusion ◽

Pedicle Screws ◽

Posterior Lumbar Interbody Fusion ◽

Incomplete Fusion ◽

Complete Fusion ◽

Spinal Diseases ◽

Titanium Cage ◽

Local Bone ◽

Autologous Bone

Abstract Background Autologous bone has been used for posterior lumbar intervertebral fusion (PLIF). However, harvesting autologous bone graft is associated with donor site complications. We previously developed a hydroxyapatite/collagen (HAp/Col) composite as an osteoconductive artificial bone, characterized by having a highly porous structure with sponge‐like elasticity. This study aims to investigate the effectiveness of HAp/Col composite with bone marrow aspirate (BMA) as a graft substitute in PLIF for the treatment of lumbar spinal diseases. Methods This study prospectively investigated patients who received one-level PLIF. For the interbody fusion, two titanium cages were inserted. On the one side of interbody space, HAp/Col composite incorporated with BMA filling the titanium cage was grafted. On the other side, local bone graft (LBG) harvested during decompressive laminotomy was grafted and then one-level instrumentation using pedicle screws was performed. The target levels were at L2/3 in 2 cases, L3/4 in 3 cases, L4/5 in 36 cases, and L5/S in 5 cases. We evaluated clinical symptoms and radiological outcomes of 46 patients and compared the fusion status of HAp/Col composite with that of LBG. Results The 1-year postoperative CT evaluation demonstrated that, in the HAp/Col, a complete fusion was observed in 38 patients (82.6%), whereas in the LBG, a complete fusion was observed in 35 patients (76.1%). There were no statistical differences between the HAp/Col and LBG. In the HAp/Col, incomplete fusion was observed in five patients (10.9%) and non-fusion in two patients (4.3%), and in the LBG, incomplete fusion was observed in nine patients (19.6%) and non-fusion in two patients (4.3%). At 2 years after the surgery, complete fusion increased to 44 patients (95.7%) in the HAp/Col and 41 patients (89.1%) in the LBG. There were no significant differences in the clinical scores for lumbar spine between patients with fusion and non-fusion. Conclusions The HAp/Col composite with BMA in the titanium cage can be effectively used as an alternative to conventional autologous LBG for intervertebral spinal fusion. Trial registration University hospital Medical Information Network, UMIN000045010, July 30th, 2021, Retrospectively registered, https://www.umin.ac.jp/english/.

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