scholarly journals The Role of Tumor Microenvironment in Mycosis Fungoides and Sézary Syndrome

2021 ◽  
Vol 33 (6) ◽  
pp. 487
Author(s):  
Zhaorui Liu ◽  
Xuesong Wu ◽  
Sam T. Hwang ◽  
Jie Liu
Keyword(s):  
Tumor Microenvironment ◽  
Mycosis Fungoides ◽  
Sézary Syndrome ◽  
Sezary Syndrome

scholarly journals The Role of Tumor Microenvironment in the Pathogenesis of Sézary Syndrome

2022 ◽  
Vol 23 (2) ◽  
pp. 936
Author(s):  
Denis Miyashiro ◽  
Bruno de Castro e Souza ◽  
Marina Passos Torrealba ◽  
Kelly Cristina Gomes Manfrere ◽  
Maria Notomi Sato ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Immune Dysregulation ◽  
Sézary Syndrome ◽  
Sezary Syndrome ◽  
Immunologic Response ◽  
T Cell Lymphomas ◽  
Sézary Cells ◽  
Peripheral Blood Involvement ◽  
Malignant T Cells

Sézary syndrome is an aggressive leukemic variant of cutaneous T-cell lymphomas, characterized by erythroderma, lymphadenopathy, and peripheral blood involvement by CD4+ malignant T-cells. The pathogenesis of Sézary syndrome is not fully understood. However, the course of the disease is strongly influenced by the tumor microenvironment, which is altered by a combination of cytokines, chemokines, and growth factors. The crosstalk between malignant and reactive cells affects the immunologic response against tumor cells causing immune dysregulation. This review focuses on the interaction of malignant Sézary cells and the tumor microenvironment.

scholarly journals The current management of mycosis fungoides and Sézary syndrome and the role of radiotherapy: Principles and indications

2014 ◽  
Vol 19 (2) ◽  
pp. 77-91 ◽  
Author(s):  
Ercole Mazzeo ◽  
Laura Rubino ◽  
Michela Buglione ◽  
Paolo Antognoni ◽  
Stefano Maria Magrini ◽  
...  
Keyword(s):  
Mycosis Fungoides ◽  
Sézary Syndrome ◽  
Sezary Syndrome ◽  
Current Management

Tumor microenvironment in mycosis fungoides and Sézary syndrome

2016 ◽  
Vol 28 (1) ◽  
pp. 88-96 ◽  
Author(s):  
Belen Rubio Gonzalez ◽  
Jasmine Zain ◽  
Steven T. Rosen ◽  
Christiane Querfeld
Keyword(s):  
Tumor Microenvironment ◽  
Mycosis Fungoides ◽  
Sézary Syndrome ◽  
Sezary Syndrome

Mycosis fungoides? Sezary syndrome

1970 ◽  
Vol 101 (2) ◽  
pp. 244-246 ◽  
Author(s):  
H. H. Roenigk
Keyword(s):  
Mycosis Fungoides ◽  
Sézary Syndrome ◽  
Sezary Syndrome
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