scholarly journals Comparison of the effectiveness of topical silicone gel and corticosteroid cream on the pfannenstiel scar prevention — a randomized controlled trial

2017 ◽  
Vol 88 (11) ◽  
pp. 591-598 ◽  
Author(s):  
Elif Meseci ◽  
Semra Kayatas ◽  
Murat Api ◽  
Aysen Boza ◽  
Muzaffer Seyhan Cikman
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Silicone Gel ◽  
Scar Prevention ◽  
Topical Silicone Gel

O5.4 Topical silicone gel versus placebo in promoting the maturation of burn scars; a randomized controlled trial

Burns ◽  
2011 ◽  
Vol 37 ◽  
pp. S4 ◽  
Author(s):  
M.B.A. Van der Wal ◽  
P.P.M. Van Zuijlen ◽  
P. Van de Ven ◽  
E. Middelkoop
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Silicone Gel ◽  
Topical Silicone Gel

Topical Silicone Gel versus Placebo in Promoting the Maturation of Burn Scars: A Randomized Controlled Trial

2010 ◽  
Vol 126 (2) ◽  
pp. 524-531 ◽  
Author(s):  
Martijn B. A. van der Wal ◽  
Paul P. van Zuijlen ◽  
Peter van de Ven ◽  
Esther Middelkoop
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Silicone Gel ◽  
Topical Silicone Gel

Reply: Topical Silicone Gel versus Placebo in Promoting the Maturation of Burn Scars: A Randomized Controlled Trial—The Pivotal Role of Statistics

2011 ◽  
Vol 128 (2) ◽  
pp. 607
Author(s):  
Martijn B. A. van der Wal ◽  
Paul P. van Zuijlen ◽  
Peter van de Ven ◽  
Esther Middelkoop
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Pivotal Role ◽  
Randomized Controlled ◽  
Silicone Gel ◽  
Topical Silicone Gel

scholarly journals Effectiveness of topical silicone gel and pressure garment therapy for burn scar prevention and management in children: a randomized controlled trial

2019 ◽  
Vol 34 (1) ◽  
pp. 120-131 ◽  
Author(s):  
Jodie Wiseman ◽  
Robert S Ware ◽  
Megan Simons ◽  
Steven McPhail ◽  
Roy Kimble ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Burn Injury ◽  
Controlled Trial ◽  
Research Centre ◽  
Burn Scar ◽  
Randomized Controlled ◽  
Silicone Gel ◽  
Pressure Garment Therapy ◽  
Scar Management ◽  
Topical Silicone Gel

Objective: To determine the effectiveness of silicone and pressure garments (alone and in combination) in children receiving scar management post-burn. Design: Multicentre, parallel-group, randomized controlled trial. Setting: Hospital outpatient clinics, colocated research centre, or the participant’s home. Participants: Children (0–18 years) referred for burn scar management. Interventions: Participants were randomized to (1) topical silicone gel only, (2) pressure garment therapy only, or (3) combined topical silicone gel and pressure garment therapy. Main measures: Primary outcomes included scar thickness and itch intensity at the primary end-point of six months post-burn injury. The outcome assessor and data analyst were blinded for scar thickness. Results: Participants ( N = 153; silicone n = 51, pressure n = 49, combined n = 53) had a median (inter-quartile range) age of 4.9 (1.6, 10.2) years and percent total body surface area burn of 1% (0.5%, 3%) and were 65% male. At six months post-burn injury, intention-to-treat analysis identified thinner scars in the silicone ( n = 51 scar sites) compared to the combined group ( n = 48 scar sites; mean difference (95% confidence interval) = –0.04 cm (–0.07, –0.00), P = 0.05). No other between-group differences were identified for scar thickness or itch intensity at six months post-burn. Conclusion: No difference was identified in the effectiveness of silicone and pressure interventions alone. No benefit to a combined silicone and pressure intervention was identified for the prevention and management of abnormal scarring in children at six months post-burn injury, compared to the silicone or pressure interventions alone.

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