Distortion-product otoacoustic emission phase shift test (Shift-DPOAE) – methodology of measurements and interpretation of results in example cases

2020 ◽  
Vol 8 (4) ◽  
pp. 1-5
Author(s):  
Magdalena Lachowska ◽  
Monika Prus-Ostaszewska ◽  
Kazimierz Niemczyk
Keyword(s):  
Phase Shift ◽  
Healthy Subjects ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Distortion Product ◽  
Ménière's Disease ◽  
Interpretation Of Results

Aim: The aim was to present methodology and interpretation of results of phase shift distortion-product otoacoustic emissions (Shift-DPOAE) in healthy subjects and patients with Meniere’s disease in remission stage and at the time of attack. Material and methods: Shift-DPOAE was performed in two healthy subjects without any otologic or neurologic problems and in six patients diagnosed with Meniere’s disease. Results obtained in eight subjects are oresented. The following tests were performed in all subjects: detailed otoscopy, impedance audiometry, pure tone audiometry, DPOAE, and Shift-DPOAE. Results: The normal Shift-DPOAE results obtained in two healthy subjects as well as the normal (two subjects) and abnormal (four subjects) Shift-DPOAE results obtained in patients with Meniere's disease are presented in order to thoroughly discuss the methodology and interpretation of the Shift-DPOAE study. Conclusions: The Shift-OAE is a promising diagnostic tool with great clinical potential in the diagnosis and monitoring of Meniere's disease in patients whose hearing has not yet been damaged. This examination is completely non-invasive, it can be carried out immediately after an attack of the disease with symptoms present at the time of the test, and it takes just a few minutes.

Does Migraine-Associated Vertigo Share a Common Pathophysiology With Meniere's Disease? Study With Vestibular-Evoked Myogenic Potential

Cephalalgia ◽  
2009 ◽  
Vol 29 (12) ◽  
pp. 1259-1266 ◽  
Author(s):  
T Murofushi ◽  
H Ozeki ◽  
A Inoue ◽  
A Sakata
Keyword(s):  
Healthy Subjects ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Vestibular Evoked Myogenic Potentials ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Vestibular Evoked Myogenic Potential ◽  
Ménière's Disease ◽  
Disease Study

To clarify if migraine-associated vertigo (MAV) and Meniere's disease (MD) share a common pathophysiology, vestibular-evoked myogenic potentials (VEMP) were measured in 11 patients with MAV, 11 with unilateral MD and eight healthy subjects. As acoustic stimuli, tone bursts (TB; 250, 500, 1000 and 2000 Hz) were presented. In healthy subjects, 500-Hz TB evoked the largest amplitude. To quantify this tendency, 500-1000 VEMP slope was calculated, and 500-1000 VEMP slope was the smallest on the affected side of MD patients. Among the 11 MD patients, five had significantly decreased 500-1000 VEMP asymmetry (shift of the tuning to 1000 Hz). Three of the 11 MAV patients also showed a significantly decreased 500-1000 VEMP slope. This finding suggests that MAV might share a common pathophysiology with MD. In addition to this finding, four of the other eight MAV patients showed prolonged p13 latencies. This suggests that MAV could consist of patients with different lesion sites.

scholarly journals The “hype” of hydrops in classifying vestibular disorders: a narrative review

2020 ◽  
Vol 267 (S1) ◽  
pp. 197-211
Author(s):  
Marly F. J. A. van der Lubbe ◽  
Akshayaa Vaidyanathan ◽  
Vincent Van Rompaey ◽  
Alida A. Postma ◽  
Tjasse D. Bruintjes ◽  
...  
Keyword(s):  
Vestibular Schwannoma ◽  
Healthy Subjects ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Vestibular Disorders ◽  
Menière's Disease ◽  
Ménière's Disease

Abstract Background Classifying and diagnosing peripheral vestibular disorders based on their symptoms is challenging due to possible symptom overlap or atypical clinical presentation. To improve the diagnostic trajectory, gadolinium-based contrast-enhanced magnetic resonance imaging of the inner ear is nowadays frequently used for the in vivo confirmation of endolymphatic hydrops in humans. However, hydrops is visualized in both healthy subjects and patients with vestibular disorders, which might make the clinical value of hydrops detection on MRI questionable. Objective To investigate the diagnostic value of clinical and radiological features, including the in vivo visualization of endolymphatic hydrops, for the classification and diagnosis of vestibular disorders. Methods A literature search was performed in February and March 2019 to estimate the prevalence of various features in healthy subjects and in common vestibular disorders to make a graphical comparison between healthy and abnormal. Results Of the features studied, hydrops was found to be a highly prevalent feature in Menière’s disease (99.4%). Though, hydrops has also a relatively high prevalence in patients with vestibular schwannoma (48.2%) and in healthy temporal bones (12.5%) as well. In patients diagnosed with (definite or probable) Menière’s disease, hydrops is less frequently diagnosed by magnetic resonance imaging compared to the histological confirmation (82.3% versus 99.4%). The mean prevalence of radiologically diagnosed hydrops was 31% in healthy subjects, 28.1% in patients with vestibular migraine, and 25.9% in patients with vestibular schwannoma. An interesting finding was an absolute difference in hydrops prevalence between the two diagnostic techniques (histology and radiology) of 25.2% in patients with Menière’s disease and 29% in patients with vestibular schwannoma. Conclusions Although the visualization of hydrops has a high diagnostic value in patients with definite Menière’s disease, it is important to appreciate the relatively high prevalence of hydrops in healthy populations and other vestibular disorders. Endolymphatic hydrops is not a pathognomic phenomenon, and detecting hydrops should not directly indicate a diagnosis of Menière’s disease. Both symptom-driven and hydrops-based classification systems have disadvantages. Therefore, it might be worth to explore features “beyond” hydrops. New analysis techniques, such as Radiomics, might play an essential role in (re)classifying vestibular disorders in the future.

Distortion product otoacoustic emissions in Ménière's disease

2000 ◽  
Vol 29 (2) ◽  
pp. 111-119 ◽  
Author(s):  
Giancarlo Cianfrone ◽  
Giovanni Ralli ◽  
Mariantonietta Fabbricatore ◽  
Giancarlo Altissimi ◽  
Giuseppe Nola
Keyword(s):  
Otoacoustic Emissions ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Distortion Product Otoacoustic Emissions ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Distortion Product ◽  
Ménière's Disease
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