scholarly journals Penalized Spline Joint Models for Longitudinal and Time-To-Event Data

Author(s):  
Huong Thi Thu Pham ◽  
Hoa Pham

2020 ◽  
Vol 26 (1) ◽  
pp. 49-68
Author(s):  
Huong Thi Thu Pham ◽  
Hoa Pham ◽  
Darfiana Nur

AbstractBayesian approaches have been used in the literature to estimate the parameters for joint models of longitudinal and time-to-event data. The main aim of this paper is to analyze the impact of prior distributions on estimating parameters in a proposed fully Bayesian analysis setting for the penalized spline joint models. To achieve this aim, the joint posterior distribution of parameters in survival and longitudinal submodels is presented. The Markov chain Monte Carlo (MCMC) algorithm is then proposed, which consists of the Gibbs sampler (GS) and Metropolis Hastings (MH) algorithms to sample for the target conditional posterior distributions. The prior sensitivity analysis for the baseline hazard rate and association parameters is performed through simulation studies and a case study.



2016 ◽  
Vol 46 (20) ◽  
pp. 10294-10314 ◽  
Author(s):  
Pham Thi Thu Huong ◽  
Darfiana Nur ◽  
Alan Branford












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