scholarly journals Fulminant Clostridium difficile Colitis Successfully Treated by Loop Ileostomy with Colonic Lavage Following Transverse Colectomy and Distal Gastrectomy

2020 ◽  
Vol 53 (3) ◽  
pp. 246-256
Author(s):  
Motoaki Yokoyama ◽  
Hiroyuki Nagai ◽  
Rei Matsumoto ◽  
Toru Saito ◽  
Satoshi Nozawa ◽  
...  
2020 ◽  
Vol 2020 (7) ◽  
Author(s):  
Maura Morgan ◽  
Timothy Farrell ◽  
Gordian U Ndubizu ◽  
Timothy J Farrell

Abstract Clostridium difficile infection (CDI) is a common nosocomial sequela in patients treated with antibiotics. Surgical intervention is indicated in fulminant cases. However, the mortality associated with total colectomy and end ileostomy is high. Previous reports have indicated that surgical intervention for severe complicated CDI with formation of a loop ileostomy leading to the diversion of fecal stream followed by colonic lavage can be beneficial in treating severe CDI. This procedure is known as the Pittsburgh protocol and has been reported to decrease the mortality and the need for a total colectomy in patients with severe complicated CDI. In this case, we present a 75-year-old female with refractory CDI. In her treatment, we adapted the Pittsburgh protocol and utilized a 20-French MIC gastrostomy tube to recreate the ileocecal valve and control the colonic lavage without retrograde flow.


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