Clostridium difficile infection following reversal of loop ileostomy: an uncommon but significant complication

2021 ◽  
Author(s):  
Danielle Taylor ◽  
Hinna Azher ◽  
Richard Gartrell ◽  
Justin M. Yeung
Keyword(s):  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Loop Ileostomy ◽  
Significant Complication

scholarly journals Colonic lavage in treatment of refractory Clostridium difficile infection: an adaptation of the Pittsburgh protocol

2020 ◽  
Vol 2020 (7) ◽  
Author(s):  
Maura Morgan ◽  
Timothy Farrell ◽  
Gordian U Ndubizu ◽  
Timothy J Farrell
Keyword(s):  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Surgical Intervention ◽  
Total Colectomy ◽  
Loop Ileostomy ◽  
Ileocecal Valve ◽  
Retrograde Flow ◽  
Fecal Stream ◽  
Colonic Lavage ◽  
And Control

Abstract Clostridium difficile infection (CDI) is a common nosocomial sequela in patients treated with antibiotics. Surgical intervention is indicated in fulminant cases. However, the mortality associated with total colectomy and end ileostomy is high. Previous reports have indicated that surgical intervention for severe complicated CDI with formation of a loop ileostomy leading to the diversion of fecal stream followed by colonic lavage can be beneficial in treating severe CDI. This procedure is known as the Pittsburgh protocol and has been reported to decrease the mortality and the need for a total colectomy in patients with severe complicated CDI. In this case, we present a 75-year-old female with refractory CDI. In her treatment, we adapted the Pittsburgh protocol and utilized a 20-French MIC gastrostomy tube to recreate the ileocecal valve and control the colonic lavage without retrograde flow.

Self-Administered Home Series Fecal “Minitransplants” for Recurrent Clostridium difficile Infection on a Rectal Remnant

2015 ◽  
Vol 24 (4) ◽  
pp. 531-533 ◽  
Author(s):  
Daniel Popa ◽  
Mihaela Laszlo ◽  
Lidia Ciobanu ◽  
Elena Ucenic ◽  
Manuela Mihalache ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Toxic Megacolon ◽  
Fecal Microbiota ◽  
Recurrent Infections ◽  
Resonance Imaging ◽  
Vaginal Infection ◽  
Fecal Microbiota Transplant ◽  
Recurrent Clostridium Difficile Infection

A fecal microbiota transplant has proved to be an extremely effective method for patients with recurrent infections with Clostridium difficile. We present the case of a 65-year-old female patient with multiple Clostridium difficile infection (CDI) relapses on the rectal remnant, post-colectomy for a CDI-related toxic megacolon. The patient also evidenced associated symptomatic Clostridium difficile vaginal infection. She was successfully treated with serial fecal “minitransplants” (self-administered at home) and metronidazole ovules.Abbreviations: GI: gastrointestinal; MRI: magnetic resonance imaging; CDI: Clostridium difficile infection; FMT: fecal microbiota transplant.

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