This review categorizes the active intermediates generated from denitrogenation of vinyl azides under different reaction conditions, and highlights newly discovered transformations of vinyl azides that lead to convenient syntheses of N-heterocycles.
The Smiles rearrangement has undergone a renaissance in recent years providing new avenues for non-canonical arylation techniques in both the radical and polar regimes. This Short Review will discuss recent applications of the reaction (from 2017 onwards), including its relevance to areas such as heterocycle synthesis, functionalisation of alkenes and alkynes as well as glimpses at new directions for the field.
Reactivities of vinyl azides and their recent applications in nitrogen heterocycle synthesis