scholarly journals Scandium(III)-Catalyzed Aza-Michael Addition of in Situ Generated ortho-Quinone Methides with Amines: An Efficient Access to Betti Base Derivatives

2019 ◽  
Vol 39 (3) ◽  
pp. 709
Author(s):  
Shuo Zhang ◽  
Ning Zhao ◽  
Qinggang Li ◽  
Jiaqi Zhang ◽  
Zitong Hou ◽  
...  
Keyword(s):  
Michael Addition ◽  
Quinone Methides ◽  
Betti Base ◽  
Efficient Access

An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface

2019 ◽  
Vol 55 (18) ◽  
pp. 2668-2671 ◽  
Author(s):  
Xianghui Liu ◽  
Kai Wang ◽  
Wengang Guo ◽  
Yan Liu ◽  
Can Li
Keyword(s):  
Michael Addition ◽  
Organic Base ◽  
Quinone Methides

Highly enantioselective organocatalytic Michael addition of tritylthiol to N-o-QM intermediates generated in situ at the H2O/DCM interface is presented.

scholarly journals Squaramide-Catalyzed Enantioselective Michael Addition of Pyrazol-3- ones to ortho-Quinone Methides

2020 ◽  
Vol 17 (11) ◽  
pp. 837-844
Author(s):  
Laura Carceller-Ferrer ◽  
Gonzalo Blay ◽  
José R. Pedro ◽  
Carlos Vila
Keyword(s):  
Michael Addition ◽  
Enantiomeric Excess ◽  
Quinone Methides

A bifunctional squaramide catalyzed the enantioselective Michael addition of pyrazol-3- ones to ortho-quinone methides, generated in situ from 2-(1-tosylalkyl)phenols is presented. The corresponding chiral pyrazolones are obtained with good to excellent yields (27-98%) and enantiomeric excess (14-99% ee).

In situ generation and reactions of p-(trifluoromethyl)benzyl electrophiles: an efficient access to p-(trifluoromethyl)benzyl compounds

2017 ◽  
Vol 53 (10) ◽  
pp. 1668-1671 ◽  
Author(s):  
Jinhuan Dong ◽  
Shuang Xin ◽  
Yanqing Wang ◽  
Ling Pan ◽  
Qun Liu
Keyword(s):  
Michael Addition ◽  
Efficient Access ◽  
Three Component Reaction ◽  
In Situ Generation

A new three-component reaction, namely condensation–anti-Michael addition–aromatization, enabling the construction of benzylic compounds is disclosed.

Organocatalytic Enantioselective 1,6-aza -Michael Addition of Isoxazolin-5-ones to p -Quinone Methides

2020 ◽  
Vol 2020 (5) ◽  
pp. 627-630 ◽  
Author(s):  
Ricardo Torán ◽  
Carlos Vila ◽  
Amparo Sanz-Marco ◽  
M. Carmen Muñoz ◽  
José R. Pedro ◽  
...  
Keyword(s):  
Michael Addition ◽  
Quinone Methides
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