scholarly journals Linear IgA bullous dermatosis

2021 ◽  
Vol 97 (4) ◽  
pp. 199-202
Author(s):  
Kamilla Koszorú ◽  
◽  
Miklós Sárdy
Keyword(s):  
Diagnostic Tests ◽  
Line Treatment ◽  
Clinical Diagnostic ◽  
Bullous Dermatosis ◽  
Mucosal Involvement ◽  
Linear Iga Bullous Dermatosis ◽  
String Of Pearls ◽  
Benign Course

Linear IgA bullous dermatosis is a rare autoimmune blistering disorder, afecting both children and adults. The goal of this review is to summarize the clinical, diagnostic, and therapeutic aspects of the disease. Subepidermal, tense blisters, urticariform plaques and erosions develop on the skin, typically in a grouped pattern. Annularly arranged lesions are referred to as “cluster of jewels”, while lesions forming a linear or arched pattern are named “string of pearls”. Mucosal involvement is also present in some cases, and scarring may lead to permanent complications. Specifc autoimmune diagnostic tests are essential for the defnitive diagnosis. The frst line treatment is dapsone and the disease shows a benign course in most cases.

scholarly journals A Case of Linear IgA Bullous Dermatosis Induced by Aspirin Therapy

2020 ◽  
Author(s):  
Mohammad Nabavi ◽  
Afshin Rezaeifar ◽  
Ali Sadeghinia ◽  
Saba Arshi ◽  
Sima Bahrami ◽  
...  
Keyword(s):  
Direct Immunofluorescence ◽  
Causative Role ◽  
Drug Induced ◽  
Autoimmune Blistering Disease ◽  
Bullous Dermatosis ◽  
Causative Agents ◽  
History Of ◽  
Blistering Disease ◽  
Linear Iga Bullous Dermatosis ◽  
String Of Pearls

Linear IgA bullous dermatosis (LABD) is a rare autoimmune blistering disease that may be triggered by some diseases and medications. For the latter one, non-steroidal anti-inflammatory drugs (NSAIDs) have been identified as one of the potential causative agents to develop LABD. Here, a rare case of drug-induced LABD is introduced. A 13-month-old Iranian boy presented with a history of generalized blisters, displaying the classic “string of pearls” sign who was eventually diagnosed as a case of LABD. In his admission, he was diagnosed whit Mucocutaneous lymph node syndrome and treated with aspirin.  Some features like appearing the characteristic lesions one week following the administration of aspirin, rapid clearance of lesions after the withdrawal of the drug, and reappearance of new lesions after readministration of aspirin were highly suggestive of aspirin-induced LABD. To establish the diagnosis, we used the “Naranjo probability score” which determined the probable causative role of aspirin. The diagnosis was confirmed by showing the positive IgA deposition in the basement membrane zone in a direct immunofluorescence study of the skin biopsy. The child was treated with dapsone with dramatical response to the drug.

scholarly journals Vancomycin‐induced linear IgA bullous dermatosis ( LABD )—an atypical presentation

2019 ◽  
Vol 7 (5) ◽  
pp. 1091-1093 ◽  
Author(s):  
Lorena Visentainer ◽  
Juliana Yumi Massuda ◽  
Maria Letícia Cintra ◽  
Renata Ferreira Magalhães
Keyword(s):  
Atypical Presentation ◽  
Bullous Dermatosis ◽  
Linear Iga Bullous Dermatosis

scholarly journals A Case of Neonatal Linear IgA Bullous Dermatosis with Severe Eye Involvement

2015 ◽  
Vol 95 (8) ◽  
pp. 1015-1017 ◽  
Author(s):  
L Romani ◽  
A Diociaiuti ◽  
P D'Argenio ◽  
M Hachem ◽  
L Gargiullo ◽  
...  
Keyword(s):  
Bullous Dermatosis ◽  
Linear Iga Bullous Dermatosis ◽  
Eye Involvement
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