scholarly journals Epidermotropic pagetoid spread and squamous cell carcinoma in situ in the overlying epidermis of Merkel cell carcinoma

2014 ◽  
Vol 5 (2) ◽  
pp. 210-211
Author(s):  
Toshiyuki Yamamoto
2016 ◽  
Vol 20 (6) ◽  
pp. 563-566 ◽  
Author(s):  
Maria A. McGowan ◽  
Matthew F. Helm ◽  
Michelle B. Tarbox

Background:Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous neoplasm that has exhibited an exponential increase in incidence in the past 3 decades. Combined MCC and cutaneous squamous cell carcinoma (SCC/MCC) is an uncommon variant of MCC that exhibits worse prognosis than pure MCC.Objective:To describe the clinical presentation, dermoscopy, and histology of an unusual subtype of combined SCC/MCC.Methods and Results:A 73-year-old white woman presented with an ulcerated and violaceous 10-mm plaque on her right jawline that had been present for 2 to 3 months. On dermoscopy, the lesion was predominantly milky pink to red with peripheral crusting and large-caliber polymorphous vessels. Histology revealed SCC in situ above and adjacent to MCC. The tumor was excised with clear margins, and sentinel lymph node scintography was negative for nodal involvement.


2018 ◽  
Vol 44 (5) ◽  
pp. 613-620 ◽  
Author(s):  
Andrew J. Matsumoto ◽  
Adam R. Schmitt ◽  
Logan M. Skelley ◽  
Christian L. Baum

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