scholarly journals Author response: Cerebellar Purkinje cell activity modulates aggressive behavior

2020 ◽  
Author(s):  
Skyler L Jackman ◽  
Christopher H Chen ◽  
Heather L Offermann ◽  
Iain R Drew ◽  
Bailey M Harrison ◽  
...  
Keyword(s):  
Purkinje Cell ◽  
Aggressive Behavior ◽  
Cell Activity ◽  
Cerebellar Purkinje Cell ◽  
Author Response

Effects of intravenous cocaine administration on cerebellar Purkinje cell activity

2000 ◽  
Vol 407 (1-2) ◽  
pp. 91-100 ◽  
Author(s):  
Carlos A Jiménez-Rivera ◽  
Omayra Segarra ◽  
Zoraya Jiménez ◽  
Barry D Waterhouse
Keyword(s):  
Purkinje Cell ◽  
Cell Activity ◽  
Cerebellar Purkinje Cell ◽  
Cocaine Administration ◽  
Intravenous Cocaine

scholarly journals Cerebellar Purkinje cell activity modulates aggressive behavior

2020 ◽  
Author(s):  
Skyler L. Jackman ◽  
Christopher H. Chen ◽  
Heather L. Offermann ◽  
Iain R. Drew ◽  
Bailey M. Harrison ◽  
...  
Keyword(s):  
Purkinje Cell ◽  
Aggressive Behavior ◽  
Purkinje Cells ◽  
Motor Function ◽  
Cell Activity ◽  
Cerebellar Vermis ◽  
Cognitive Behaviors ◽  
Affective Behaviors ◽  
Cerebellar Purkinje Cells ◽  
The Impact

AbstractAlthough the cerebellum is traditionally associated with balance and motor function, it also plays wider roles in affective and cognitive behaviors. Evidence suggests that the cerebellar vermis may regulate aggressive behavior, though the cerebellar circuits and patterns of activity that influence aggression remain unclear. We used optogenetic methods to bidirectionally modulate the activity of spatially-delineated cerebellar Purkinje cells to evaluate the impact on aggression in mice. Increasing Purkinje cell activity in the vermis significantly reduced the frequency of attacks in a resident-intruder assay. Reduced aggression was not a consequence of impaired motor function, because optogenetic stimulation did not alter motor performance. In complementary experiments, optogenetic inhibition of Purkinje cells in the vermis increased the frequency of attacks. These results establish Purkinje cell activity in the cerebellar vermis regulates aggression, and further support the importance of the cerebellum in driving affective behaviors that could contribute to neurological disorders.

Propofol depresses cerebellar Purkinje cell activity via activation of GABAA and glycine receptors in vivo in mice

2015 ◽  
Vol 764 ◽  
pp. 87-93 ◽  
Author(s):  
Ri Jin ◽  
Heng Liu ◽  
Wen-Zhe Jin ◽  
Jin-Di Shi ◽  
Qing-Hua Jin ◽  
...  
Keyword(s):  
Purkinje Cell ◽  
Cell Activity ◽  
Cerebellar Purkinje Cell ◽  
Glycine Receptors

scholarly journals Impact of NMDA Receptor Overexpression on Cerebellar Purkinje Cell Activity and Motor Learning

eNeuro ◽  
2018 ◽  
Vol 5 (1) ◽  
pp. ENEURO.0270-17.2018 ◽  
Author(s):  
Elisa Galliano ◽  
Martijn Schonewille ◽  
Saša Peter ◽  
Mandy Rutteman ◽  
Simone Houtman ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Motor Learning ◽  
Purkinje Cell ◽  
Cell Activity ◽  
Cerebellar Purkinje Cell

Inverse-Dynamics Representation of Eye Movements by Cerebellar Purkinje Cell Activity during Short-Latency Ocular-Following Responses

1996 ◽  
Vol 781 (1 Lipids and Sy) ◽  
pp. 314-321 ◽  
Author(s):  
KENJI KAWANO ◽  
MUNETAKA SHIDARA ◽  
AYA TAKEMURA ◽  
YUKA INOUE ◽  
HIROAKI GOMI ◽  
...  
Keyword(s):  
Eye Movements ◽  
Purkinje Cell ◽  
Inverse Dynamics ◽  
Cell Activity ◽  
Short Latency ◽  
Cerebellar Purkinje Cell ◽  
Ocular Following
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