scholarly journals Primary Cutaneous Cryptococcosis in a Patient on Fingolimod: A Case Report

Cureus ◽  
2021 ◽  
Author(s):  
Deena Dahshan ◽  
Sofanit A Dessie ◽  
Jonathan Cuda ◽  
Elie Khalil
2013 ◽  
Vol 31 (2) ◽  
pp. 90-93 ◽  
Author(s):  
Ying-Yi Lu ◽  
Chieh-Shan Wu ◽  
Chien-Hui Hong

2017 ◽  
Vol 23 (2) ◽  
pp. 297-299 ◽  
Author(s):  
Adam F Carpenter ◽  
Shikha J Goodwin ◽  
Peter F Bornstein ◽  
Andrew J Larson ◽  
Christine K Markus

Background: Fingolimod is an oral disease-modifying therapy for relapsing forms of multiple sclerosis, which acts by sequestering lymphocytes within lymph nodes. Objective: To describe a case of extrapulmonary cryptococcosis in a patient taking fingolimod. Methods: Case report. Results: A 47-year-old man developed a non-healing skin lesion approximately 16 months after starting treatment with fingolimod. Biopsy revealed cryptococcosis. Fingolimod was discontinued and the lesion resolved with antifungal therapy. Conclusion: Despite few reported opportunistic infections in the pivotal clinical trials and first few years post-marketing, there has been a recent increase in reported AIDS-defining illnesses in patients taking fingolimod. Neurologists should be alert for opportunistic infections in their patients using this medication.


Dermatology ◽  
2002 ◽  
Vol 204 (2) ◽  
pp. 145-149 ◽  
Author(s):  
F. Revenga ◽  
J.F. Paricio ◽  
F.J. Merino ◽  
T. Nebreda ◽  
T. Ramírez ◽  
...  

1988 ◽  
Vol 15 (6) ◽  
pp. 385-392 ◽  
Author(s):  
L Barfield ◽  
D. Lacobelli ◽  
K. Hashimoto

2015 ◽  
Vol 185 (4) ◽  
pp. 959-963 ◽  
Author(s):  
Y. Liu ◽  
H. qunpeng ◽  
X. Shutian ◽  
X. Honglang

2001 ◽  
Vol 24 (10) ◽  
pp. 816-819 ◽  
Author(s):  
S. Takahashi ◽  
H. Iijima ◽  
Yuji Moriwaki ◽  
T. Yamamoto ◽  
S. Matsuoka ◽  
...  

2008 ◽  
Vol 21 (2) ◽  
pp. 463-466 ◽  
Author(s):  
V. Devirgiliis ◽  
V. Panasiti ◽  
R.G. Borroni ◽  
M. Rossi ◽  
M. Curzio ◽  
...  

Mycoses ◽  
2001 ◽  
Vol 44 (9-10) ◽  
pp. 419-421 ◽  
Author(s):  
L. Ramos ◽  
C. López ◽  
C. Gómez ◽  
S. Mathurín ◽  
A. Mateo

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