scholarly journals First Branchial Cleft Anomalies: Awareness Is Key

Cureus ◽  
2021 ◽  
Author(s):  
Javier Ash ◽  
Oliver H Sanders ◽  
Tarik Abed ◽  
Jonathan Philpott
2016 ◽  
Vol 126 (9) ◽  
pp. 2147-2150 ◽  
Author(s):  
Michela Piccioni ◽  
Marco Bottazzoli ◽  
Nader Nassif ◽  
Stefania Stefini ◽  
Piero Nicolai

1992 ◽  
Vol 106 (2) ◽  
pp. 137-143 ◽  
Author(s):  
G. R. Ford ◽  
A. Balakrishnan ◽  
J. N. G. Evans ◽  
C. M. Bailey

AbstractWe present a retrospective study of 106 patients with branchial cleft and pouch anomalies who presented to the Hospital for Sick Children between 1948 and 1990. The relevant embryology of the branchial apparatus is summarized and a theoretical description of individual anomalies given.Second branchial cleft sinuses were the most common anomalies, and the majority were managed simply, with adequate excision and a low recurrence rate. Five cases of first branchial cleft anomalies are presented, emphasizing the delay in diagnosis, the need for complete excision to prevent recurrence, and for a parotidectomy incision to protect the facial nerve from damage. The two third branchial pouch anomalies presented with a cystic neck swelling, one with recurrent infection and discharge, and the other with stridor. In both, the diagnosis was made at operation. The single fourth branchial pouch cyst was an unexpected finding in a patient with stridor.


2018 ◽  
Vol 190 (44) ◽  
pp. E1307-E1307
Author(s):  
Petros Koltsidopoulos ◽  
Charalampos Skoulakis

2021 ◽  
Vol 8 (11) ◽  
pp. 375-377
Author(s):  
Ashoka Nand Thakur ◽  
Priyambada .

Branchial cleft anomalies are well described, with the second arch anomaly being the commonest. Remains of cervical sinus of His may persist as a branchial cyst. A branchial sinus is formed when 2nd branchial arch fails to meet the 5th pharyngeal arch. Peak age for presentation of branchial cysts is in the third decade and that of the congenital sinuses and fistulae is at birth. The association of a branchial cyst with branchial sinus is very rare. We are presenting two cases had branchial cyst along with branchial sinus. It was managed successfully with complete excision. Histopathological examination confirmed the association. Keywords: Branchial Sinus, Branchial cyst,


2011 ◽  
Vol 279 (1727) ◽  
pp. 224-229 ◽  
Author(s):  
Jo Richardson ◽  
Takanori Shono ◽  
Masataka Okabe ◽  
Anthony Graham

The operculum is a large flap consisting of several flat bones found on the side of the head of bony fish. During development, the opercular bones form within the second pharyngeal arch, which expands posteriorly and comes to cover the gill-bearing arches. With the evolution of the tetrapods and the assumption of a terrestrial lifestyle, it was believed that the operculum was lost. Here, we demonstrate that an embryonic operculum persists in amniotes and that its early development is homologous with that of teleosts. As in zebrafish, the second pharyngeal arch of the chick embryo grows disproportionately and comes to cover the posterior arches. We show that the developing second pharyngeal arch in both chick and zebrafish embryos express orthologous genes and require shh signalling for caudal expansion. In amniotes, however, the caudal edge of the expanded second arch fuses to the surface of the neck. We have detailed how this process occurs and also demonstrated a requirement for thyroid signalling here. Our results thus demonstrate the persistence of an embryonic opercular flap in amniotes, that its fusion mirrors aspects of amphibian metamorphosis and gives insights into the origin of branchial cleft anomalies in humans.


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