scholarly journals Evidence of Post Trabeculectomy Optic Nerve Reperfusion by OCT Angiography

2020 ◽  
pp. 35-39
Author(s):  
Jigyasa Sahu
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Nerve Fiber ◽  
Structural Parameters ◽  
Visual Fields ◽  
Vessel Density ◽  
Oct Angiography ◽  
Prognostic Indicators ◽  
Fiber Layer ◽  
Nerve Fiber Layer

Aim: To describe a case of glaucoma which showed increase in optical coherence tomography (OCT) angiographic vessel densities after intraocular pressure reduction suggesting reperfusion of optic nerve. Presentation of Case: A 55 year old female with primary open angle glaucoma was taken up for trabeculectomy in view of inadequate control of intraocular pressure (IOP) despite maximal medical therapy. In addition to routine glaucoma assessment by visual fields and nerve fiber layer assessment by OCT, OCT angiographic evaluation of peripapillary vessel density was done preoperatively. Three months after trabeculectomy, her intraocular pressure decreased from 35mmHg to 14mmHg. Compared with the preoperative baseline value, the vessel density increased significantly in all quadrants after three months from surgery as demonstrated by OCT angiography. Discussion: This case report suggests that decreased optic nerve head perfusion due to high IOP can be reversed by reduction of IOP. Conclusion: Vascular parameters like angiographic vessel density can show reversible changes as decreased blood flow reinstates and thus can be better prognostic indicators than structural parameters like OCT retinal nerve fiber layer (RNFL) in glaucoma patients.

Macular and Optic Nerve Head Vessel Density and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma

Ophthalmology ◽  
2018 ◽  
Vol 125 (11) ◽  
pp. 1720-1728 ◽  
Author(s):  
Sasan Moghimi ◽  
Linda M. Zangwill ◽  
Rafaella C. Penteado ◽  
Kyle Hasenstab ◽  
Elham Ghahari ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Optic Nerve Head ◽  
Vessel Density ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Retinal Nerve Fiber

scholarly journals Association between Rates of Retinal Nerve Fiber Layer Thinning after Intraocular Pressure–Lowering Procedures and Disc Hemorrhage

2020 ◽  
Vol 3 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Huiyuan Hou ◽  
Sasan Moghimi ◽  
Linda M. Zangwill ◽  
James A. Proudfoot ◽  
Tadamichi Akagi ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Disc Hemorrhage ◽  
Nerve Fiber Layer ◽  
Pressure Lowering ◽  
Retinal Nerve Fiber

Changes in Intraocular Pressure and Corneal and Retinal Nerve Fiber Layer Thicknesses in Hypothyroidism

2005 ◽  
Vol 15 (5) ◽  
pp. 556-561 ◽  
Author(s):  
U.A. Bahçeci ◽  
Ş. Özdek ◽  
Z. Pehlivanli ◽  
I. Yetkin ◽  
M. Önol
Keyword(s):  
Intraocular Pressure ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Scanning Laser ◽  
Fiber Layer ◽  
Serum Free ◽  
Correlation Test ◽  
Nerve Fiber Layer ◽  
The Mean ◽  
Spearman’S Correlation

Purpose To evaluate the changes in intraocular pressure (IOP), corneal thickness (CT), and retinal nerve fiber layer thickness (RNFLT) in patients with hypothyroidism before and after treatment. Methods A complete ophthalmic examination including visual acuity, IOP, anterior segment, and fundus examination together with CT and RNFLT measurements were performed for each patient with newly diagnosed hypothyroidism, at the initial diagnosis and the third and ninth months of the L-thyroxine treatment. Wilcoxon signed rank test and Spearman's correlation test were used for statistical evaluation of the results. Results A total of 56 eyes of 28 patients were included in the study. The mean IOP and CT values were found to decrease with medical treatment (p=0.000). There was no significant change in any of the RNFLT parameters measured with scanning laser Polarimeter after L-thyroxine treatment (Wilcoxon, p>0.05). The change in IOP levels was not correlated with the change in thyroid hormone levels (Spearman's correlation test, p>0.05). The mean increase in serum free T3 and serum free T4 levels and the mean decrease in serum TSH levels at the ninth month of the therapy were found to be correlated with the decrease in CT in the left eyes (Spearman's correlation test, R>0.4 and p<0.05). Conclusions Hypothyroidism seems to cause a reversible increase in CT and IOP. IOP changes may be secondary to CT changes. RNFLT parameters measured with scanning laser Polarimeter do not seem to be affected by hypothyroidism. When the CT is taken into account and the IOPs corrected for CT, the prevalence of glaucoma in hypothyroidism may not be as high as previously reported. This issue should be taken into account while assessing glaucoma in patients with hypothyroidism.

scholarly journals Effect of optic nerve head drusen on nerve fiber layer thickness11The authors have no proprietary interest in the development of this or competing instruments.

Ophthalmology ◽  
1998 ◽  
Vol 105 (5) ◽  
pp. 878-885 ◽  
Author(s):  
Shiyoung Roh ◽  
Robert J Noecker ◽  
Joel S Schuman ◽  
Thomas R Hedges ◽  
John J Weiter ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Nerve Fiber ◽  
Optic Nerve Head ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Optic Nerve Head Drusen
Sign in / Sign up

Export Citation Format

Share Document