We summarize the progress of the nickel-catalyzed alkyne difunctionalization reaction for the synthesis of tri- and tetrasubstituted olefins, with an emphasis on the strategy and control of stereochemistry.
Stereoselective Synthesis of Tri- and Tetrasubstituted Olefins via 1,6-Additions of Diazo Compounds and Their Precursors to p-Quinone Methides