When teeming rare earth treated steels the nozzle blockage occurred so frequently that seriously interferes the application of RE in steels. In this study we tried to investigate the relationship between the wettablility of 16MnRE steel and nozzle materials. The results showed that the weakest wettability of steel liquid was observed on fused silica among the six nozzle materials. Next came zircon and high-alumina nozzle. It has no obvious difference between the 16MnRE steels when final deoxidized containing and not containing Al addition. The wettability of 10Ti steel was weaker than 16MnRE steels on zircon nozzle. The clay nozzle was corroded by the precipitate from steel liquid.