This chapter discusses familiarity as a dependent variable, specifically focusing on memory errors that may occur when an eyewitness makes a familiarity judgment after witnessing a crime. The chapter highlights the link between familiarity memory errors and wrongful conviction. The chapter describes various factors within the justice system that may lead to familiarity errors, such as the concept of the mugshot commitment effect, mere prior exposure effects, and the presence of a bystander during the commission of the crime. Next, the chapter describes why familiarity errors occur and how they may be prevented by considering issues with source monitoring, unconscious transference, and stereotyping. Finally, the chapter describes other ways in which familiarity may lead to a wrongful conviction, such as alibis from familiar others.