We classify real hypersurfaces with isometric Reeb flow in the complex hyperbolic quadrics [Formula: see text], [Formula: see text]. We show that [Formula: see text] is even, say [Formula: see text], and any such hypersurface becomes an open part of a tube around a [Formula: see text]-dimensional complex hyperbolic space [Formula: see text] which is embedded canonically in [Formula: see text] as a totally geodesic complex submanifold or a horosphere whose center at infinity is [Formula: see text]-isotropic singular. As a consequence of the result, we get the nonexistence of real hypersurfaces with isometric Reeb flow in odd-dimensional complex quadrics [Formula: see text], [Formula: see text].