negative estrogen receptor status
Recently Published Documents


TOTAL DOCUMENTS

3
(FIVE YEARS 0)

H-INDEX

3
(FIVE YEARS 0)

2018 ◽  
Vol 25 (6) ◽  
Author(s):  
A. Bouchard-Fortier ◽  
N. N. Baxter ◽  
R. Sutradhar ◽  
K. Fernandes ◽  
X. Camacho ◽  
...  

Background and Objectives Contralateral prophylactic mastectomy (cpm) has been increasingly common among women with unilateral invasive breast cancer (ibca) even though the data that support it are limited. Using a population-based cohort, the objectives of the present study were to describe factors predictive of cpm in young women (≤35 years) with ibca and to evaluate the impact of the procedure on mortality.Methods All women diagnosed during 1994–2003 and treated with cpm were identified from the Ontario Cancer Registry. Logistic regression was used to identify patient and tumour factors associated with the use of cpm. Multivariate analyses were used to assess the effect of cpm on recurrence and mortality.Results Of 614 women identified, 81 underwent cpm (13.2%). On multivariable analysis, factors associated with cpm included negative lymph node status, negative estrogen receptor status, and initial breast-conserving surgery with re-excision. At follow-up, breast cancer–specific mortality was similar for women who did and did not undergo cpm.Conclusions Use of cpm in young women with ibca (compared with non-use) was not associated improved breast cancer–specific mortality. Factors found to be predictive of cpm were negative lymph node status, negative estrogen receptor status, and initial breast-conserving surgery followed by re-excision.



2006 ◽  
Vol 14 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Dora Fuckar ◽  
Andrea Dekanic ◽  
Sanja Stifter ◽  
Elvira Mustac ◽  
Mira Krstulja ◽  
...  




Sign in / Sign up

Export Citation Format

Share Document