A Comprehensive Guide to Toxicology in Preclinical Drug Development
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9780123878151

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Genetic Toxicology Testing

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00007-1 ◽

2013 ◽

pp. 141-166

Author(s):

John Nicolette

Keyword(s):

Genetic Toxicology

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Preclinical Development of Non-Oncogenic Drugs (Small and Large Molecules)

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00022-8 ◽

2013 ◽

pp. 517-542 ◽

Author(s):

John B. Colerangle

Keyword(s):

Preclinical Development ◽

Large Molecules

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Contemporary Practices in Core Safety Pharmacology Assessments

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00006-x ◽

2013 ◽

pp. 107-140

Author(s):

Theodore J. Baird ◽

David V. Gauvin ◽

Jill A. Dalton

Keyword(s):

Safety Pharmacology

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Role of Study Director and Study Monitor in Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00031-9 ◽

2013 ◽

pp. 747-757 ◽

Author(s):

Colleen Johnson ◽

Stephen Frantz

Keyword(s):

Drug Development ◽

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Overview of the Nonclinical Development Strategies and Class-Effects of Oligonucleotide-Based Therapeutics

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00026-5 ◽

2013 ◽

pp. 647-664 ◽

Author(s):

Husam S. Younis ◽

Michael Templin ◽

Lawrence O. Whitely ◽

Douglas Kornbrust ◽

Tae-Won Kim ◽

...

Keyword(s):

Development Strategies

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Acute, Sub-Acute, Sub-Chronic and Chronic General Toxicity Testing for Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00005-8 ◽

2013 ◽

pp. 87-105 ◽

Author(s):

Kevin H. Denny ◽

Christopher W. Stewart

Keyword(s):

Drug Development ◽

Toxicity Testing ◽

General Toxicity ◽

Preclinical Drug Development

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Juvenile Toxicity Testing to Support Clinical Trials in the Pediatric Population

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00015-0 ◽

2013 ◽

pp. 383-394

Author(s):

Bjorn A. Thorsrud ◽

Ali S. Faqi ◽

Melissa J. Beck ◽

LaRonda L. Morford

Keyword(s):

Clinical Trials ◽

Pediatric Population ◽

Toxicity Testing

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Developmental and Reproductive Toxicology

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00013-7 ◽

2013 ◽

pp. 335-364 ◽

Author(s):

Ali S. Faqi ◽

Alan Hoberman ◽

Elise Lewis ◽

Donald Stump

Keyword(s):

Reproductive Toxicology

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Preclinical Evaluation of Carcinogenicity using the Rodent Two-Year Bioassay

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00017-4 ◽

2013 ◽

pp. 423-436 ◽

Author(s):

David L. McCormick

Keyword(s):

Preclinical Evaluation

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Toxicometabolomics

A Comprehensive Guide to Toxicology in Preclinical Drug Development ◽

10.1016/b978-0-12-387815-1.00034-4 ◽

2013 ◽

pp. 807-825

Author(s):

Michael V. Milburn ◽

John A. Ryals ◽

Lining Guo

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