Iris Ring Melanoma With Extrascleral Extension

2012 ◽  
Vol 130 (10) ◽  
pp. 1334
Author(s):  
Sherif Khedr ◽  
David Lewis ◽  
Daniel Albert ◽  
Mark Lucarelli ◽  
Heather Potter
Keyword(s):  
Ring Melanoma

scholarly journals A Case of Iris Melanocytoma Demonstrating Diffuse Melanocytic Proliferation with Uncontrolled Intraocular Pressure

2017 ◽  
Vol 8 (1) ◽  
pp. 190-194 ◽  
Author(s):  
Mami Kusunose ◽  
Yuji Sakino ◽  
Yoshihiro Noda ◽  
Tsutomu Daa ◽  
Toshiaki Kubota
Keyword(s):  
Electron Microscopy ◽  
Intraocular Pressure ◽  
Tumor Cells ◽  
Trabecular Meshwork ◽  
Light And Electron Microscopy ◽  
Secondary Glaucoma ◽  
Pigment Dispersion ◽  
Large Tumor ◽  
History Of ◽  
Ring Melanoma

We report a rare case with histologically proven melanocytoma of the iris that demonstrated diffuse melanocytic proliferation with uncontrolled secondary glaucoma and investigate the etiology of the intraocular pressure elevation. The patient was a 78-year-old man with a history of darkened iris of his left eye. The intraocular pressure was 39 mm Hg. A slit-lamp examination showed a diffuse darkened iris, and a gonioscopic examination revealed open angle with circumferential heavy pigmentation. There was no pigment dispersion of the anterior chamber and no pigment deposition of the cornea. We suspected malignant ring melanoma in the left eye and enucleated it. The globe was examined with light and electron microscopy. Light microscopy revealed the presence of heavily pigmented tumor cells in the iris, ciliary body, trabecular meshwork, and Schlemm’s canal. A bleached preparation showed large tumor cells with central and paracentral nuclei without mitosis. Electron microscopy of the trabecular meshwork revealed melanin-bearing tumor cells invading the intertrabecular spaces, and the melanin granules were not phagocytosed in the trabecular cells. The mechanical obstruction of the aqueous flow by the tumor cells may be a major cause of secondary glaucoma in eyes with iris melanocytoma presenting diffuse proliferation.

scholarly journals Ring melanoma of the iris and ciliary body.

1985 ◽  
Vol 69 (7) ◽  
pp. 514-518 ◽  
Author(s):  
W Omulecki ◽  
M Pruszczynski ◽  
J Borowski
Keyword(s):  
Ciliary Body ◽  
Ring Melanoma

Diffuse Malignant Ring Melanoma of the Iris and Ciliary Body

1979 ◽  
Vol 178 (4) ◽  
pp. 235-238 ◽  
Author(s):  
Olga Litričin
Keyword(s):  
Ciliary Body ◽  
Ring Melanoma

Ring melanoma of the anterior chamber angle: a report of fourteen cases

2001 ◽  
Vol 132 (3) ◽  
pp. 336-342 ◽  
Author(s):  
Hakan Demirci ◽  
Carol L Shields ◽  
Jerry A Shields ◽  
Ralph C Eagle ◽  
Santosh Honavar
Keyword(s):  
Anterior Chamber ◽  
Anterior Chamber Angle ◽  
Ring Melanoma ◽  
Chamber Angle

Signet Ring Melanoma, S-100 Negative

1989 ◽  
Vol 13 (6) ◽  
pp. 522-523 ◽  
Author(s):  
Franco Bonetti ◽  
Romano Colombari ◽  
Giuseppe Zamboni ◽  
Marco Chilosi ◽  
Franco Legnami
Keyword(s):  
Signet Ring ◽  
S 100 ◽  
Ring Melanoma

Ring melanoma of the iris

1985 ◽  
Vol 7 (3-4) ◽  
pp. 161-167 ◽  
Author(s):  
Peter C. Donders
Keyword(s):  
Ring Melanoma

Case Study 163 Ring Melanoma

2013 ◽  
pp. 371-372
Author(s):  
Roger P. Harrie ◽  
Cynthia J. Kendall
Keyword(s):  
Ring Melanoma

scholarly journals Malignant transformation of iris melanocytoma to iris ring melanoma

2007 ◽  
Vol 91 (11) ◽  
pp. 1571-1572 ◽  
Author(s):  
M. S Sagoo ◽  
P. Mruthyunjaya ◽  
I. Cree ◽  
P. J Luthert ◽  
J. L Hungerford
Keyword(s):  
Malignant Transformation ◽  
Ring Melanoma

scholarly journals Isolated Ocular Sarcoidosis Mimicking Ring Melanoma

2019 ◽  
Vol 6 (3) ◽  
pp. 180-183
Author(s):  
Carsten Faber ◽  
Rasmus Ejstrup ◽  
Karine Madsen ◽  
Steffen Heegaard ◽  
David Scheie ◽  
...  
Keyword(s):  
Ciliary Body ◽  
Frozen Section ◽  
Granulomatous Inflammation ◽  
Ultrasound Biomicroscopy ◽  
Anterior Chamber Angle ◽  
Ocular Sarcoidosis ◽  
Sarcoid Granuloma ◽  
Subtenon Injection ◽  
Ring Melanoma ◽  
Work Up

We report the case of a 25-year-old female, who presented with a large, pale tumor of her ciliary body that extended to >180° of the anterior chamber angle. All preoperative examinations including ultrasound biomicroscopy, scleral transillumination, and MRI indicated melanoma. A thorough systemic work-up was negative. A diagnosis of ring melanoma was suspected, and the patient was scheduled for enucleation. However, perioperative frozen section indicated granulomatous inflammation. The enucleation was cancelled, and a subtenon injection of triamcinolone was administered, which resulted in the disappearance of the tumor. Together, the findings meet the criteria for the diagnosis of isolated ocular sarcoidosis. This case demonstrates that a sarcoid granuloma can mimic all clinical features of a ring melanoma. Therefore, a biopsy should be done before destructive surgery is carried out.

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