Prognostic Value of Lymph Node Dissection in Malignant Melanoma

1980 ◽  
Vol 115 (6) ◽  
pp. 719 ◽  
Author(s):  
Constantine P. Karakousis
Keyword(s):  
Lymph Node ◽  
Malignant Melanoma ◽  
Lymph Node Dissection ◽  
Prognostic Value ◽  
Node Dissection

scholarly journals Malignant Melanoma: Current Concepts of Lymph Node Dissection

1972 ◽  
Vol 22 (4) ◽  
pp. 216-220 ◽  
Author(s):  
H. S. Goldsmith ◽  
J. P. Shah ◽  
D.-H. Kim
Keyword(s):  
Lymph Node ◽  
Malignant Melanoma ◽  
Lymph Node Dissection ◽  
Node Dissection

Ugly is not only skin deep: A case of osteogenic melanoma.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e20009-e20009
Author(s):  
Joshua C.M. Williams ◽  
Natale Tate Sheehan ◽  
Pierre DeDelva ◽  
Jennifer Barr
Keyword(s):  
Lymph Node ◽  
Malignant Melanoma ◽  
Lymph Node Dissection ◽  
Lower Lobe ◽  
Lymph Node Involvement ◽  
Node Dissection ◽  
Inguinal Lymph Node Dissection ◽  
Left Lower Extremity ◽  
Node Involvement ◽  
Initial Biopsy

e20009 Background: Although the incidence of malignant melanoma is high, the incidence of metaplastic malignant melanoma is low. Within the various subtypes of malignant metaplastic melanoma, the manifestation of osteogenic melanoma remains a rarer event. Current review of the literature reveals only 12 reported cases. Of these reported cases, scant discussion is made on treatment whereas the histopathology is discussed in great detail. Methods: We present the case of a 64 year old Caucasian man that was diagnosed with synchronous tumors of the foot and lung. Initial biopsy of the foot revealed metastatic osteogenic melanoma. As a result of the initial biopsy results and imaging, the patient underwent a right lower lobe resection and lymph node dissection followed by a left lower extremity Pirigoff’s amputation and inguinal lymph node dissection. Results: Immunohistochemical staining of the extirpated tissue from the lung revealed strong reactivity to S100, vimentin, Sox10, diffuse reactivity to low molecular weight cytokeratin and HMB-45/MART-1 and no lymph node involvement. Whereas the IHC of the extirpated tissue of the left foot remained consistent with the initial biopsy of strong reactivity to S100 and MART-1 and negative to pancytokeratins, CD34, Desmin, and SMA. Conclusions: Given the features of the patient’s pathology and resected metastatic disease, he was administered adjuvant alpha interferon therapy.

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