scholarly journals Efficacy of Ketogenic Diet, Modified Atkins Diet, and Low Glycemic Index Therapy Diet Among Children With Drug-Resistant Epilepsy

2020 ◽  
Vol 174 (10) ◽  
pp. 944
Author(s):  
Vishal Sondhi ◽  
Anuja Agarwala ◽  
Ravindra M. Pandey ◽  
Biswaroop Chakrabarty ◽  
Prashant Jauhari ◽  
...  
Keyword(s):  
Ketogenic Diet ◽  
Glycemic Index ◽  
Drug Resistant ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Drug Resistant Epilepsy ◽  
Low Glycemic Index

scholarly journals Dietary therapy in childhood epilepsy, an overview

2014 ◽  
Vol 01 (01) ◽  
pp. 027-035 ◽  
Author(s):  
Sheffali Gulati ◽  
Biswaroop Chakrabarty
Keyword(s):  
Ketogenic Diet ◽  
Glycemic Index ◽  
Dietary Therapy ◽  
Childhood Epilepsy ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Systemic Side Effects ◽  
Low Glycemic Index Treatment ◽  
Index Treatment ◽  
Low Glycemic Index

AbstractThis review highlights the current consensus guidelines regarding use of dietary therapy in childhood epilepsy. Comprehensive search was done in the electronic database, journals, reference lists and dissertations related to the field. In childhood epilepsy, about one-third patients are medically refractory. Surgical resection is an effective modality only in a third of these cases. Dietary therapy causes upto 30–40% reduction in seizure frequency in drug refractory epilepsy. The various forms of dietary therapies described are ketogenic diet, modified Atkins diet and low glycemic index treatment. Apart from ketogenesis, the ketogenic diet also exerts its effect by modulating brain energetics and neurotransmitter circuitry. The classical ketogenic diet comprises of fat to carbohydrate ratio of 4:1 (in terms of weight in grams). Modified Atkins diet is restrictive only for carbohydrates (≤20 g per day). Low glycemic index treatment allows carbohydrate of upto 60 g per day with food items having glycemic index of less than 50. Consensus recommendations for indications and contraindications of dietary therapy in childhood epilepsy have been formulated. Moreover caution has to be warranted for various metabolic and systemic side effects described with this form of therapy. Laboratory and clinical assessment prior to initiation and periodically on therapy is recommended. A trial of dietary therapy is labeled as failure only if there is no response even after 12 weeks of therapy. There is research ongoing globally on dietary therapy with preliminary encouraging reports in status epilepticus and other neurological conditions like migraine, brain tumor and autism.

Efficacy of low glycemic index diet therapy (LGIT) in children aged 2–8 years with drug-resistant epilepsy: A randomized controlled trial

2021 ◽  
Vol 171 ◽  
pp. 106574
Author(s):  
Kannan Lakshminarayanan ◽  
Anuja Agarawal ◽  
Prateek Kumar Panda ◽  
Rahul Sinha ◽  
Manjari Tripathi ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Glycemic Index ◽  
Controlled Trial ◽  
Diet Therapy ◽  
Drug Resistant ◽  
Randomized Controlled ◽  
Drug Resistant Epilepsy ◽  
Low Glycemic Index

Low glycemic index treatment in patients with drug-resistant epilepsy

2017 ◽  
Vol 39 (8) ◽  
pp. 687-692 ◽  
Author(s):  
Se Hee Kim ◽  
Hoon-Chul Kang ◽  
Eun Joo Lee ◽  
Joon Soo Lee ◽  
Heung Dong Kim
Keyword(s):  
Glycemic Index ◽  
Drug Resistant ◽  
Low Glycemic Index Treatment ◽  
Drug Resistant Epilepsy ◽  
Index Treatment ◽  
Low Glycemic Index

scholarly journals What's New in the Medical Management of Pediatric Epilepsy?

2012 ◽  
Vol 39 (S6) ◽  
pp. S30-S34
Author(s):  
Elaine C. Wirrell
Keyword(s):  
Glycemic Index ◽  
Medical Management ◽  
Pediatric Epilepsy ◽  
Modified Atkins Diet ◽  
Antiepileptic Therapy ◽  
Atkins Diet ◽  
Antiepileptic Medications ◽  
Low Glycemic Index

Epilepsy affects approximately 45 per 100,000 children per year. While many cases respond favorably to antiepileptic therapy, approximately 20% will prove to be medically intractable. This paper reviews some of the recently identified important metabolic and autoimmune etiologies for which there are specific therapies. Additionally, newer antiepileptic medications, including rufinamide, lacosamide, retigabine, eslicarbazepine and brivaracetam and newer dietary options, including the modified Atkins diet and low-glycemic index diet are discussed.

scholarly journals Ketogenic diet for epilepsy treatment

2016 ◽  
Vol 74 (10) ◽  
pp. 842-848 ◽  
Author(s):  
Letícia Pereira de Brito Sampaio
Keyword(s):  
Ketogenic Diet ◽  
Refractory Epilepsy ◽  
Medium Chain Triglyceride ◽  
Modified Atkins Diet ◽  
The Past ◽  
Atkins Diet ◽  
Low Carbohydrate ◽  
History Of ◽  
Index Treatment ◽  
Low Glycemic Index

ABSTRACT The ketogenic diet (KD), a high-fat, low-carbohydrate, and adequate-protein diet is an established, effective nonpharmacologic treatment option for intractable childhood epilepsy. The KD was developed in 1921 and even though it has been increasingly used worldwide in the past decade, many neurologists are not familiar with this therapeutic approach. In the past few years, alternative and more flexible KD variants have been developed to make the treatment easier and more palatable while reducing side effects and making it available to larger group of refractory epilepsy patients. This review summarizes the history of the KD and the principles and efficacy of the classic ketogenic diet, medium-chain triglyceride(s) (MCT) ketogenic diet, modified Atkins diet, and low glycemic index treatment.

Modified Atkins diet for drug-resistant epilepsy and the risk of urolithiasis

2021 ◽  
Author(s):  
M. F. Nassar ◽  
O. F. El-Rashidy ◽  
M. H. Abdelhamed ◽  
M. O. Shata
Keyword(s):  
Drug Resistant ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Drug Resistant Epilepsy

scholarly journals Dietary therapies for epilepsy in low resource settings: challenges and successes

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Suvasini Sharma
Keyword(s):  
Ketogenic Diet ◽  
Refractory Epilepsy ◽  
Low Cost ◽  
Low Resource Settings ◽  
Low Resource ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Low Carbohydrate ◽  
Drug Resistant Epilepsy ◽  
Restricted Protein Diet

The Ketogenic Diet (KD) is a high fat, low carbohydrate and restricted protein diet which has been used for the treatment of drug resistant epilepsy in children. It is considered the treatment of choice for refractory nonsurgical epilepsy in children. However, despite this being a very useful and relatively simple treatment, children from developing countries have not been able to benefit as much as their counterparts in more privileged settings. In this article, the challenges faced by pediatric neurologists and parents who wish to use the diet in children with refractory epilepsy are discussed, and also the simple low cost innovations which can be used to overcome these challenges are suggested. The evolution from the use of the classic ketogenic diet to the flexible use of the modified Atkins diet in low resource settings will be discussed.

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