Modified Atkins Diet vs Low Glycemic Index Treatment for Drug-Resistant Epilepsy in Children: An Open Label, Randomized Controlled Trial

2021 ◽  
Vol 58 (9) ◽  
pp. 815-819
Author(s):  
Surbhi Gupta ◽  
Surekha Dabla ◽  
Jaya Shankar Kaushik
Keyword(s):  
Controlled Trial ◽  
Drug Resistant ◽  
Open Label ◽  
Modified Atkins Diet ◽  
Randomized Controlled ◽  
Atkins Diet ◽  
Low Glycemic Index Treatment ◽  
Drug Resistant Epilepsy ◽  
Index Treatment ◽  
Low Glycemic Index

Efficacy of low glycemic index diet therapy (LGIT) in children aged 2–8 years with drug-resistant epilepsy: A randomized controlled trial

2021 ◽  
Vol 171 ◽  
pp. 106574
Author(s):  
Kannan Lakshminarayanan ◽  
Anuja Agarawal ◽  
Prateek Kumar Panda ◽  
Rahul Sinha ◽  
Manjari Tripathi ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Glycemic Index ◽  
Controlled Trial ◽  
Diet Therapy ◽  
Drug Resistant ◽  
Randomized Controlled ◽  
Drug Resistant Epilepsy ◽  
Low Glycemic Index

Low glycemic index treatment in patients with drug-resistant epilepsy

2017 ◽  
Vol 39 (8) ◽  
pp. 687-692 ◽  
Author(s):  
Se Hee Kim ◽  
Hoon-Chul Kang ◽  
Eun Joo Lee ◽  
Joon Soo Lee ◽  
Heung Dong Kim
Keyword(s):  
Glycemic Index ◽  
Drug Resistant ◽  
Low Glycemic Index Treatment ◽  
Drug Resistant Epilepsy ◽  
Index Treatment ◽  
Low Glycemic Index

scholarly journals Dietary therapy in childhood epilepsy, an overview

2014 ◽  
Vol 01 (01) ◽  
pp. 027-035 ◽  
Author(s):  
Sheffali Gulati ◽  
Biswaroop Chakrabarty
Keyword(s):  
Ketogenic Diet ◽  
Glycemic Index ◽  
Dietary Therapy ◽  
Childhood Epilepsy ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Systemic Side Effects ◽  
Low Glycemic Index Treatment ◽  
Index Treatment ◽  
Low Glycemic Index

AbstractThis review highlights the current consensus guidelines regarding use of dietary therapy in childhood epilepsy. Comprehensive search was done in the electronic database, journals, reference lists and dissertations related to the field. In childhood epilepsy, about one-third patients are medically refractory. Surgical resection is an effective modality only in a third of these cases. Dietary therapy causes upto 30–40% reduction in seizure frequency in drug refractory epilepsy. The various forms of dietary therapies described are ketogenic diet, modified Atkins diet and low glycemic index treatment. Apart from ketogenesis, the ketogenic diet also exerts its effect by modulating brain energetics and neurotransmitter circuitry. The classical ketogenic diet comprises of fat to carbohydrate ratio of 4:1 (in terms of weight in grams). Modified Atkins diet is restrictive only for carbohydrates (≤20 g per day). Low glycemic index treatment allows carbohydrate of upto 60 g per day with food items having glycemic index of less than 50. Consensus recommendations for indications and contraindications of dietary therapy in childhood epilepsy have been formulated. Moreover caution has to be warranted for various metabolic and systemic side effects described with this form of therapy. Laboratory and clinical assessment prior to initiation and periodically on therapy is recommended. A trial of dietary therapy is labeled as failure only if there is no response even after 12 weeks of therapy. There is research ongoing globally on dietary therapy with preliminary encouraging reports in status epilepticus and other neurological conditions like migraine, brain tumor and autism.

scholarly journals Efficacy of Ketogenic Diet, Modified Atkins Diet, and Low Glycemic Index Therapy Diet Among Children With Drug-Resistant Epilepsy

2020 ◽  
Vol 174 (10) ◽  
pp. 944
Author(s):  
Vishal Sondhi ◽  
Anuja Agarwala ◽  
Ravindra M. Pandey ◽  
Biswaroop Chakrabarty ◽  
Prashant Jauhari ◽  
...  
Keyword(s):  
Ketogenic Diet ◽  
Glycemic Index ◽  
Drug Resistant ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Drug Resistant Epilepsy ◽  
Low Glycemic Index

scholarly journals External trigeminal nerve stimulation for drug resistant epilepsy: A randomized controlled trial

2020 ◽  
Vol 13 (5) ◽  
pp. 1245-1253
Author(s):  
Francisco Gil-López ◽  
Teresa Boget ◽  
Isabel Manzanares ◽  
Antonio Donaire ◽  
Estefanía Conde-Blanco ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Trigeminal Nerve ◽  
Nerve Stimulation ◽  
Controlled Trial ◽  
Drug Resistant ◽  
Randomized Controlled ◽  
Trigeminal Nerve Stimulation ◽  
Drug Resistant Epilepsy

scholarly journals Randomized controlled trial of trigeminal nerve stimulation for drug-resistant epilepsy

Neurology ◽  
2013 ◽  
Vol 80 (9) ◽  
pp. 786-791 ◽  
Author(s):  
C. M. DeGiorgio ◽  
J. Soss ◽  
I. A. Cook ◽  
D. Markovic ◽  
J. Gornbein ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Trigeminal Nerve ◽  
Nerve Stimulation ◽  
Controlled Trial ◽  
Drug Resistant ◽  
Randomized Controlled ◽  
Trigeminal Nerve Stimulation ◽  
Drug Resistant Epilepsy

scholarly journals Ketogenic diet for epilepsy treatment

2016 ◽  
Vol 74 (10) ◽  
pp. 842-848 ◽  
Author(s):  
Letícia Pereira de Brito Sampaio
Keyword(s):  
Ketogenic Diet ◽  
Refractory Epilepsy ◽  
Medium Chain Triglyceride ◽  
Modified Atkins Diet ◽  
The Past ◽  
Atkins Diet ◽  
Low Carbohydrate ◽  
History Of ◽  
Index Treatment ◽  
Low Glycemic Index

ABSTRACT The ketogenic diet (KD), a high-fat, low-carbohydrate, and adequate-protein diet is an established, effective nonpharmacologic treatment option for intractable childhood epilepsy. The KD was developed in 1921 and even though it has been increasingly used worldwide in the past decade, many neurologists are not familiar with this therapeutic approach. In the past few years, alternative and more flexible KD variants have been developed to make the treatment easier and more palatable while reducing side effects and making it available to larger group of refractory epilepsy patients. This review summarizes the history of the KD and the principles and efficacy of the classic ketogenic diet, medium-chain triglyceride(s) (MCT) ketogenic diet, modified Atkins diet, and low glycemic index treatment.

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