scholarly journals Expanding Dietary Therapy Beyond the Classic Ketogenic Diet: On the Use of the Modified Atkins Diet and Low Glycemic Index Treatment in Pediatric Epilepsy

2021 ◽  
Vol 58 (9) ◽  
pp. 811-812
Author(s):  
Robyn Whitney ◽  
Rajesh Ramachandran Nair
Keyword(s):  
Ketogenic Diet ◽  
Glycemic Index ◽  
Dietary Therapy ◽  
Pediatric Epilepsy ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Low Glycemic Index Treatment ◽  
Index Treatment ◽  
Low Glycemic Index

scholarly journals Dietary therapy in childhood epilepsy, an overview

2014 ◽  
Vol 01 (01) ◽  
pp. 027-035 ◽  
Author(s):  
Sheffali Gulati ◽  
Biswaroop Chakrabarty
Keyword(s):  
Ketogenic Diet ◽  
Glycemic Index ◽  
Dietary Therapy ◽  
Childhood Epilepsy ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Systemic Side Effects ◽  
Low Glycemic Index Treatment ◽  
Index Treatment ◽  
Low Glycemic Index

AbstractThis review highlights the current consensus guidelines regarding use of dietary therapy in childhood epilepsy. Comprehensive search was done in the electronic database, journals, reference lists and dissertations related to the field. In childhood epilepsy, about one-third patients are medically refractory. Surgical resection is an effective modality only in a third of these cases. Dietary therapy causes upto 30–40% reduction in seizure frequency in drug refractory epilepsy. The various forms of dietary therapies described are ketogenic diet, modified Atkins diet and low glycemic index treatment. Apart from ketogenesis, the ketogenic diet also exerts its effect by modulating brain energetics and neurotransmitter circuitry. The classical ketogenic diet comprises of fat to carbohydrate ratio of 4:1 (in terms of weight in grams). Modified Atkins diet is restrictive only for carbohydrates (≤20 g per day). Low glycemic index treatment allows carbohydrate of upto 60 g per day with food items having glycemic index of less than 50. Consensus recommendations for indications and contraindications of dietary therapy in childhood epilepsy have been formulated. Moreover caution has to be warranted for various metabolic and systemic side effects described with this form of therapy. Laboratory and clinical assessment prior to initiation and periodically on therapy is recommended. A trial of dietary therapy is labeled as failure only if there is no response even after 12 weeks of therapy. There is research ongoing globally on dietary therapy with preliminary encouraging reports in status epilepticus and other neurological conditions like migraine, brain tumor and autism.

scholarly journals What's New in the Medical Management of Pediatric Epilepsy?

2012 ◽  
Vol 39 (S6) ◽  
pp. S30-S34
Author(s):  
Elaine C. Wirrell
Keyword(s):  
Glycemic Index ◽  
Medical Management ◽  
Pediatric Epilepsy ◽  
Modified Atkins Diet ◽  
Antiepileptic Therapy ◽  
Atkins Diet ◽  
Antiepileptic Medications ◽  
Low Glycemic Index

Epilepsy affects approximately 45 per 100,000 children per year. While many cases respond favorably to antiepileptic therapy, approximately 20% will prove to be medically intractable. This paper reviews some of the recently identified important metabolic and autoimmune etiologies for which there are specific therapies. Additionally, newer antiepileptic medications, including rufinamide, lacosamide, retigabine, eslicarbazepine and brivaracetam and newer dietary options, including the modified Atkins diet and low-glycemic index diet are discussed.

scholarly journals Ketogenic diet for epilepsy treatment

2016 ◽  
Vol 74 (10) ◽  
pp. 842-848 ◽  
Author(s):  
Letícia Pereira de Brito Sampaio
Keyword(s):  
Ketogenic Diet ◽  
Refractory Epilepsy ◽  
Medium Chain Triglyceride ◽  
Modified Atkins Diet ◽  
The Past ◽  
Atkins Diet ◽  
Low Carbohydrate ◽  
History Of ◽  
Index Treatment ◽  
Low Glycemic Index

ABSTRACT The ketogenic diet (KD), a high-fat, low-carbohydrate, and adequate-protein diet is an established, effective nonpharmacologic treatment option for intractable childhood epilepsy. The KD was developed in 1921 and even though it has been increasingly used worldwide in the past decade, many neurologists are not familiar with this therapeutic approach. In the past few years, alternative and more flexible KD variants have been developed to make the treatment easier and more palatable while reducing side effects and making it available to larger group of refractory epilepsy patients. This review summarizes the history of the KD and the principles and efficacy of the classic ketogenic diet, medium-chain triglyceride(s) (MCT) ketogenic diet, modified Atkins diet, and low glycemic index treatment.

Efficacy, safety, and tolerability of the low glycemic index treatment in pediatric epilepsy

Epilepsia ◽  
2009 ◽  
Vol 50 (5) ◽  
pp. 1118-1126 ◽  
Author(s):  
David A. Muzykewicz ◽  
David A. Lyczkowski ◽  
Naureen Memon ◽  
Kerry D. Conant ◽  
Heidi H. Pfeifer ◽  
...  
Keyword(s):  
Glycemic Index ◽  
Pediatric Epilepsy ◽  
Low Glycemic Index Treatment ◽  
Index Treatment ◽  
Low Glycemic Index

scholarly journals Efficacy of Ketogenic Diet, Modified Atkins Diet, and Low Glycemic Index Therapy Diet Among Children With Drug-Resistant Epilepsy

2020 ◽  
Vol 174 (10) ◽  
pp. 944
Author(s):  
Vishal Sondhi ◽  
Anuja Agarwala ◽  
Ravindra M. Pandey ◽  
Biswaroop Chakrabarty ◽  
Prashant Jauhari ◽  
...  
Keyword(s):  
Ketogenic Diet ◽  
Glycemic Index ◽  
Drug Resistant ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Drug Resistant Epilepsy ◽  
Low Glycemic Index

“Alternative” Ketogenic Diets

2016 ◽  
Author(s):  
Elizabeth Neal
Keyword(s):  
Ketogenic Diet ◽  
Scientific Data ◽  
Dietary Therapy ◽  
Older Children ◽  
Medium Chain ◽  
Modified Atkins Diet ◽  
Ketogenic Diets ◽  
Centennial Anniversary ◽  
Index Treatment ◽  
Low Glycemic Index

As the classical ketogenic diet fast approaches a centennial anniversary, the wider ketogenic landscape has expanded considerably both in application and implementation. Although still extensively used today, this traditional dietary therapy has been the basis for development of alternative ketogenic protocols. One ketogenic diet incorporating medium chain fatty acids is used for many children and adolescents, who benefit from the generous carbohydrate allowance facilitated by the increased ketogenic potential of medium chain triglycerides. More recently, two less restrictive dietary approaches have been developed: the low glycemic index treatment and the modified Atkins diet. These are now being used worldwide as the advantages of a more liberal ketogenic diet are recognized, especially in adults and older children, supported by an increasing body of scientific data. This chapter explores the background and evidence for use of these alternative ketogenic diets.

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