Helix-destabilizing protein (relaxing protein, relaxation protein, melting protein)

2015 ◽  
pp. 1-1
Keyword(s):  
Protein Relaxation

A decadentate Gd(III)-coordinating paramagnetic cosolvent for protein relaxation enhancement measurement

2014 ◽  
Vol 58 (3) ◽  
pp. 149-154 ◽  
Author(s):  
Xin-Hua Gu ◽  
Zhou Gong ◽  
Da-Chuan Guo ◽  
Wei-Ping Zhang ◽  
Chun Tang
Keyword(s):  
Protein Relaxation

scholarly journals The dipolar origin of protein relaxation

1968 ◽  
Vol 110 (3) ◽  
pp. 419-424 ◽  
Author(s):  
H. Hendrickx ◽  
R. Verbruggen ◽  
M. Y. Rosseneu-Motreff ◽  
V. Blaton ◽  
H. Peeters
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Axial Ratio ◽  
Ion Exchange Resin ◽  
Dielectric Dispersion ◽  
Dipole Relaxation ◽  
Ellipsoid Of Revolution ◽  
Dielectric Increment ◽  
Protein Relaxation

1. A set of parameters is proposed to check the interpretation of the dielectric behaviour of protein solutions as a rigid-dipole relaxation of prolate ellipsoids of revolution in the frequency range between 20 kHz and 10 MHz. Besides the δb-function of Scheraga, another analogous function (δa) is presented to establish size and shape of globular proteins. A study of the influence of solvent viscosity on the dielectric dispersion also gives strong evidence in favour of rigid-dipole relaxation. 2. Measurements of the dielectric dispersion of monomer solutions of bovine serum albumin and transferrin are reported. Monomers of bovine serum albumin were obtained by fractionation on Sephadex G-150. Low-conductivity solutions of both proteins are obtained by passage through an ion-exchange resin. 3. Computer analysis of the experimental dispersion curves by use of a two-term Debye dispersion gives valuable information about transferrin and leads to an axial ratio 4·5 for a prolate ellipsoid of revolution. The dielectric increment of bovine serum albumin is very low and no conclusive results have yet been obtained.

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