scholarly journals Evaluation of automatic contour propagation in T2-weighted 4DMRI for normal-tissue motion assessment using internal organ-at-risk volume (IRV)

2018 ◽  
Vol 19 (5) ◽  
pp. 598-608 ◽  
Author(s):  
Jingjing Zhang ◽  
Svetlana Markova ◽  
Alejandro Garcia ◽  
Kirk Huang ◽  
Xingyu Nie ◽  
...  

Author(s):  
S.L. Lee ◽  
J. Stewart ◽  
S.D. Myrehaug ◽  
A. Sahgal ◽  
M.E. Ruschin ◽  
...  


2017 ◽  
Vol 29 (4) ◽  
pp. 263-273 ◽  
Author(s):  
J.A. Dean ◽  
L.C. Welsh ◽  
K.H. Wong ◽  
A. Aleksic ◽  
E. Dunne ◽  
...  




2019 ◽  
Vol 20 (12) ◽  
pp. 45-53 ◽  
Author(s):  
Sangjune Lee ◽  
James Stewart ◽  
Young Lee ◽  
Sten Myrehaug ◽  
Arjun Sahgal ◽  
...  


2006 ◽  
Vol 13 (3) ◽  
pp. 108-115 ◽  
Author(s):  
O. Ballivy ◽  
W. Parker ◽  
T. Vuong ◽  
G. Shenouda ◽  
H. Patrocinio

We assessed the effect of geometric uncertainties on target coverage and on dose to the organs at risk (OARS) during intensity-modulated radiotherapy (IMRT) for head-and-neck cancer, and we estimated the required margins for the planning target volume (PTV) and the planning organ-at-risk volume (PRV). For eight headand- neck cancer patients, we generated IMRT plans with localization uncertainty margins of 0 mm, 2.5 mm, and 5.0 mm. The beam intensities were then applied on repeat computed tomography (CT) scans obtained weekly during treatment, and dose distributions were recalculated. The dose–volume histogram analysis for the repeat CT scans showed that target coverage was adequate (V100 ≥ 95%) for only 12.5% of the gross tumour volumes, 54.3% of the upper-neck clinical target volumes (CTVS), and 27.4% of the lower-neck CTVS when no margins were added for PTV. The use of 2.5-mm and 5.0-mm margins significantly improved target coverage, but the mean dose to the contralateral parotid increased from 25.9 Gy to 29.2 Gy. Maximum dose to the spinal cord was above limit in 57.7%, 34.6%, and 15.4% of cases when 0-mm, 2.5-mm, and 5.0-mm margins (respectively) were used for PRV. Significant deviations from the prescribed dose can occur during IMRT treatment delivery for headand- neck cancer. The use of 2.5-mm to 5.0-mm margins for PTV and PRV greatly reduces the risk of underdosing targets and of overdosing the spinal cord.





2004 ◽  
Vol 18 (1) ◽  
pp. 131-160 ◽  
Author(s):  
Maria Werner-Wasik ◽  
Xiaoli Yu ◽  
Lawrence B Marks ◽  
Timothy E Schultheiss


2006 ◽  
Vol 25 (11) ◽  
pp. 1472-1482 ◽  
Author(s):  
G. Hautvast ◽  
S. Lobregt ◽  
M. Breeuwer ◽  
F. Gerritsen




2021 ◽  
Vol 161 ◽  
pp. S223-S225
Author(s):  
J. Scheurleer ◽  
E.M. Vasquez Osorio ◽  
E. Assendelft ◽  
A. Bel ◽  
I. van Dijk ◽  
...  
Keyword(s):  
At Risk ◽  


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