Vinylogous Nucleophilic Substitution of the Hydroxy Group in Diarylmethanols with 3-Propenyl-2-silyloxyindoles: Towards the Synthesis of α -Alkylidene-δ -diaryl-2-oxindoles

2017 ◽  
Vol 359 (9) ◽  
pp. 1508-1514 ◽  
Author(s):  
Amol P. Jadhav ◽  
Amjad Ali ◽  
Ravi P. Singh
Keyword(s):  
Nucleophilic Substitution ◽  
Hydroxy Group

A METHOD FOR PREPARATION OF DROSERONE FROM PLUMBAGIN

INDIAN DRUGS ◽  
2013 ◽  
Vol 50 (05) ◽  
pp. 53-56
Author(s):  
G.M Ferreira ◽  
◽  
K.S. Laddha
Keyword(s):  
Nucleophilic Substitution ◽  
Spectral Data ◽  
Hydroxy Group ◽  
13C Nmr ◽  
Plumbago Zeylanica ◽  
1H And 13C Nmr ◽  
Naturally Occurring ◽  
Rp Hplc

Droserone (2,5-dihyrdoxy-3-methyl-1,4- naphthoquinone) was prepared from naturally occurring naphthoquinone plumbagin. Plumbagin was isolated from roots of Plumbago zeylanica. Plumbagin was first brominated at C-3 which was subsequently substituted with hydroxy group by a nucleophilic substitution to obtain Droserone. The synthesized compounds were characterized by IR, MS, 1H and 13C NMR spectral data. RP-HPLC was used to ascertain the purity of the obtained compound.

ChemInform Abstract: Iron(III)-Catalyzed Nucleophilic Substitution of the Hydroxy Group in Benzoin by Alcohols.

ChemInform ◽  
2012 ◽  
Vol 43 (32) ◽  
pp. no-no
Author(s):  
Anvar Mirzaei ◽  
Srijit Biswas ◽  
Joseph S. M. Samec
Keyword(s):  
Nucleophilic Substitution ◽  
Hydroxy Group

Iron(III)-Catalyzed Nucleophilic Substitution of the Hydroxy Group in Benzoin by Alcohols

Synthesis ◽  
2012 ◽  
Vol 44 (08) ◽  
pp. 1213-1218 ◽  
Author(s):  
Joseph Samec ◽  
Anvar Mirzaei ◽  
Srijit Biswas
Keyword(s):  
Nucleophilic Substitution ◽  
Hydroxy Group
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